The Clonal Selection Theory explain how the immune system can be both diverse and very specific at the same time.The theory states:
A clone is defined as a group of cells in which all daughter cells are equal in their specificity
Clonal selection theory explains how the adaptive immune system selects and amplifies immune cells (such as B cells and T cells) that are specific to antigens. When a pathogen enters the body, immune cells with receptors that match the antigen are selected for activation and proliferation, leading to a targeted immune response. This theory is fundamental to understanding how the immune system responds to infections and develops immunological memory.
False
Clonal selection is responsible for the production of a large population of identical B or T cells that specifically recognize and target a particular antigen. This process is critical for the adaptive immune system's ability to mount a targeted immune response against pathogens.
Clonal selection and differentiation of lymphocytes provide the basis for immunological memory.
Antigen challenge and clonal selection are most likely to occur in the secondary lymphoid organs, such as the lymph nodes and spleen. These organs are where antigens encounter immune cells, triggering an immune response and the selection of specific immune cell clones.
Antigen-presenting cells (APCs) are nonlymphocyte cells that play a central role in clonal selection. They present antigens to T cells, triggering the immune response and selection of specific clones of T cells that can recognize and respond to the antigen.
1. An antigen presenting cell presents antigen on Class II MHC to a Helper T cell activating it 2. At the same time a B cell that has taken up and degraded the same pathogen displays antigen on its class II 3. The activated helper T cell binds to the B cell releasing cytokines and activating it 4. The activated B cell proliferates and differentiates into: 1) memory B cells 2) antibody-secreting plasma cells that produce antibodies specific for the pathogen
Natural Selection
Darwin's theory of evolution.
Natural selection
theory of natural selection
The theory of evolution by means of natural selection.