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What is the function of DNA gyrase?

Updated: 8/11/2023
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13y ago

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DNA gyrase is a bacterial enzyme which introduces supercoils into the bacterial DNA, resulting in a highly condensed 3-dimentional struture. it is also known as Topoisomerase. Quinolones and F/Quinolones inhibit this enzyme and thus interfere with bacterial DNA replication. The enzyme is absent in humans.

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13y ago
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13y ago

Gyrase is an enzyme and is the first step in DNA replication. It unwinds the coiled DNA to relieve tension. It makes it easier for Helicase to split the 2 strands of DNA when it is flattened

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11y ago

To relieve strain on the DNA strand while helicase is unwinding the strand. An enzyme, of course.

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Q: What is the function of DNA gyrase?
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Related questions

Why is reverse gyrase called reverse gyrase?

The enzyme DNA gyrase produces negative supercoils in DNA. The "negative" refers to the directionality of the supercoil, not the electrical charge of the molecule. Reverse gyrase produces positive supercoils, meaning the DNA supercoils in the opposite direction of the negative supercoil.


What force makes DNA twist?

DNA gyrase makes it twist


What antibiotic is an inhibitor of DNA gyrase?

nalidixic acid &ciprofloxacin


What keeps DNA strands from being tangled?

Gyrase does, which relives torque after Helicase breaks the Hydrogen bonds.


What enzyme can remove or insert super coil twists into circular DNA?

The enzyme topoisomerase is used in inserting or loosing supercoiling in DNA during replication. It is of different type like gyrase, helicase etc. and are found in prokaryotes and eukaryotes respectively


What is an aminocoumarin?

An aminocoumarin is any of a class of antibiotics which act by inhibition of the DNA gyrase enzyme which is involved in bacterial cell division.


What are the major targets for antibiotics?

The most successful antibiotics hit only three targets. The targets that are usually hit are the ribosome, cell wall synthesis and DNA gyrase.


What is the function of most DNA in your body?

The function of most DNA is to build and maintain an organism.


What enzyme is responsible for breaking the hydrogen bonds between the two strands and unwinding the helix?

Helicases and gyrases both function to uncoil the supercoiling of the two DNA strands. Moreover, gyrase is responsible for adjusting the tension in the two strands so that they don't snap while unraveling.


What is the function of DNA chromosomes?

The main function of DNA chromosomes is to carry genes.


What is the function of most of the DNA in the body?

Most of the DNA in humans appears to have no genetic function.


What is the function of plasmid DNA?

Plasmids have small pockets of DNA in them.