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Why is reverse gyrase called reverse gyrase?
The enzyme DNA gyrase produces negative supercoils in DNA. The "negative" refers to the directionality of the supercoil, not the electrical charge of the molecule. Reverse gyrase produces positive supercoils, meaning the DNA supercoils in the opposite direction of the negative supercoil.
What is an extra loop of DNA that contains antibiotic resistance what gene?
An extra loop of DNA that carries antibiotic resistance genes is called a plasmid. These genes can provide bacteria with the ability to survive exposure to antibiotics.
Why are plasmids pieces of DNA?
i think each plasmid piece codes for a specific function. for example antibiotic resistance shown by antibiotic sensitive cell after a piece of plasmid that is antibiotic resistant gene recombine with cell DNA.
What keeps DNA strands from being tangled?
Enzymes called topoisomerases help to prevent DNA strands from becoming tangled. These enzymes are responsible for managing the coiling and uncoiling of the DNA double helix during processes like replication and transcription, ensuring that the strands remain untangled and functional.
How do DNA gyrases and helicases differ in their respective functions and modes of action?
Helicases are involved in the unwinding of DNA double helix at the replication fork. When one part of the DNA is unwound the other part is overwound which exerts strain. DNA gyrases introduces negative supercoiling to reduce the strain.
What force makes DNA twist?
DNA gyrase makes it twist
Why is reverse gyrase called reverse gyrase?
The enzyme DNA gyrase produces negative supercoils in DNA. The "negative" refers to the directionality of the supercoil, not the electrical charge of the molecule. Reverse gyrase produces positive supercoils, meaning the DNA supercoils in the opposite direction of the negative supercoil.
Do ciprofloxacin help with inflammation?
Depends on the cause of the inlammation - ciprofloxacin is a broad-spectrum antibiotic (it inhibits the DNA gyrase, an important enzyme for bacteria), so it might help if the inflammation is caused by bacteria without resistance against ciprofloxacin.
What is the function of DNA gyrase?
DNA gyrase is a bacterial enzyme which introduces supercoils into the bacterial DNA, resulting in a highly condensed 3-dimentional struture. it is also known as Topoisomerase. Quinolones and F/Quinolones inhibit this enzyme and thus interfere with bacterial DNA replication. The enzyme is absent in humans.
What is an aminocoumarin?
An aminocoumarin is any of a class of antibiotics which act by inhibition of the DNA gyrase enzyme which is involved in bacterial cell division.
Is penicillin an competitive inhibitor?
No, penicillin is not a competitive inhibitor. Penicillin is an antibiotic that works by interfering with the synthesis of bacterial cell walls, leading to cell death.
Is omiprazole an antibiotic?
No, omeprazole (Losec or Prilosec) has no antibiotic effect. It is a proton-pump inhibitor (PPI) used for stomach. It reduces stomach acidity production.
What enzyme can remove or insert super coil twists into circular DNA?
The enzyme topoisomerase is used in inserting or loosing supercoiling in DNA during replication. It is of different type like gyrase, helicase etc. and are found in prokaryotes and eukaryotes respectively
What are the major targets for antibiotics?
The most successful antibiotics hit only three targets. The targets that are usually hit are the ribosome, cell wall synthesis and DNA gyrase.
What is an extra loop of DNA that contains antibiotic resistance what gene?
An extra loop of DNA that carries antibiotic resistance genes is called a plasmid. These genes can provide bacteria with the ability to survive exposure to antibiotics.
What is a role of beta lactamase inhibitor?
Some bacteria produce beta lactamase enzyme, this enzyme will break the beta lactam ring structure of certain antibiotics (penicillin, cephalexin for example) rendering them ineffective against the infection. If you add a beta lactamase inhibitor to a beta lactam antibiotic (i.e clavulanaic acid added to amoxicillin) it decreases the potential of the bacteria to inactivate the antibiotic.
Why are plasmids pieces of DNA?
i think each plasmid piece codes for a specific function. for example antibiotic resistance shown by antibiotic sensitive cell after a piece of plasmid that is antibiotic resistant gene recombine with cell DNA.
