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Topoisomerase: are isomerase enzymes that act on the topology of DNA

Helicase untwists the double helix and separates the template DNA strands at the replication fork. This untwisting causes tighter twisting ahead of the replication fork, and topoisomerase helps relieve this strain

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What are the key differences between topoisomerase 1 and topoisomerase 2 in terms of their functions and mechanisms of action?

Topoisomerase 1 and topoisomerase 2 are enzymes that help manage DNA structure, but they have different functions and mechanisms. Topoisomerase 1 cuts one strand of DNA at a time to relieve tension, while topoisomerase 2 cuts both strands to untangle DNA. Additionally, topoisomerase 1 does not require ATP for its activity, whereas topoisomerase 2 does.


What role does topoisomerase play in the process of DNA replication?

Topoisomerase is an enzyme that helps relieve the tension and twisting that occurs in the DNA strands during replication. It helps to unwind the DNA double helix, allowing the replication machinery to move along the strands and copy the genetic information accurately.


What is the difference between helicase and topoisomerase?

Helicase is an enzyme that unwinds the DNA double helix during replication, while topoisomerase is an enzyme that helps relieve the twisting forces generated during DNA unwinding by helicase. Helicase moves along the DNA strand, separating the two strands, while topoisomerase cuts and rejoins the DNA strands to prevent overwinding or underwinding.


How does topoisomerase facilitate the unwinding of DNA during cellular processes?

Topoisomerase enzymes help unwind DNA by cutting and rejoining the DNA strands, allowing them to rotate and relieve tension during cellular processes like replication and transcription.


What enzyme can remove or insert super coil twists into circular DNA?

The enzyme topoisomerase is used in inserting or loosing supercoiling in DNA during replication. It is of different type like gyrase, helicase etc. and are found in prokaryotes and eukaryotes respectively

Related Questions

How does topoisomerase affect the DNA strand during DNA replication?

The topoisomerase enzyme uncoils the double helical structure of DNA during its replication to form the replication fork. In eukaryotes both posive and negative supercoils get unbind by topoisomerase I & II respectively.Topoisomerase isomerase unwinds DNA to form replication fork


What are the key differences between topoisomerase 1 and topoisomerase 2 in terms of their functions and mechanisms of action?

Topoisomerase 1 and topoisomerase 2 are enzymes that help manage DNA structure, but they have different functions and mechanisms. Topoisomerase 1 cuts one strand of DNA at a time to relieve tension, while topoisomerase 2 cuts both strands to untangle DNA. Additionally, topoisomerase 1 does not require ATP for its activity, whereas topoisomerase 2 does.


What role does topoisomerase play in the process of DNA replication?

Topoisomerase is an enzyme that helps relieve the tension and twisting that occurs in the DNA strands during replication. It helps to unwind the DNA double helix, allowing the replication machinery to move along the strands and copy the genetic information accurately.


What enzyme is responsible for breaking the hydrogen bonds between the two strands and unwinding the helix?

Helicases and gyrases both function to uncoil the supercoiling of the two DNA strands. Moreover, gyrase is responsible for adjusting the tension in the two strands so that they don't snap while unraveling.


What has the author Leonardo Salmena written?

Leonardo Salmena has written: 'The cell cycle-dependent regulation of DNA topoisomerase II[alpha] expression is mediated by proteasomal degradation'


What is the difference between helicase and topoisomerase?

Helicase is an enzyme that unwinds the DNA double helix during replication, while topoisomerase is an enzyme that helps relieve the twisting forces generated during DNA unwinding by helicase. Helicase moves along the DNA strand, separating the two strands, while topoisomerase cuts and rejoins the DNA strands to prevent overwinding or underwinding.


A researcher while working in vitro outside cell added helicase enzyme which resulted in the untwisting of the DNA helix But this untwisting led to strain ahead of the replication fork Which enzym?

The enzyme that can relieve the strain ahead of the replication fork caused by the untwisting of DNA by helicase is topoisomerase. Topoisomerase helps to relax the supercoiling of DNA that occurs during processes like DNA replication.


How does topoisomerase facilitate the unwinding of DNA during cellular processes?

Topoisomerase enzymes help unwind DNA by cutting and rejoining the DNA strands, allowing them to rotate and relieve tension during cellular processes like replication and transcription.


What are the release dates for Role Play - 2010 II?

Role Play - 2010 II was released on: USA: 6 November 2010


What enzyme can remove or insert super coil twists into circular DNA?

The enzyme topoisomerase is used in inserting or loosing supercoiling in DNA during replication. It is of different type like gyrase, helicase etc. and are found in prokaryotes and eukaryotes respectively


What is the enzyme responsible for conversion of negatively supercoiled DNA into relaxed circular DNA?

DNA topoisomerase I is the enzyme responsible for converting negatively supercoiled DNA into relaxed circular DNA by making a transient single-strand break in the DNA backbone.


What genre is EverQuest II: The Shadow Odyssey?

The genre of EverQuest II: The Shadow Odyssey is Role Playing.