C. the mice died because rough strain bacteria had been transformed to the smooth strain
S Strain ---> inject into mice ---> Mice Die R Strain ---> inject into mice ---> Mice Live Griffith was able to kill bacteria by heating them. He observed that heat-killed S Strain bacteria injected into mice did not kill them. When he S Strain (heat Killed) ---> Injected into mice ---> Mice Live S Strain ( heat Killed) + R Strain (Live) ---> Injected into mice ---> Mice Die
What did griffith observe when he injected into mice a mixture of heat-killed disease-causing bacteria and live harmless bacteria?
The difference between "walking pneumonia" and "true pneumonia".
Frederick Griffith was a British bacteriologist. In January 1928, he reported what is now known as Griffith's Experiment, the first widely accepted demonstrations of bacterial transformation, whereby a bacterium distinctly changes its form and function.
A very important characteristic about bacteria actually created live S-strain to exist in the dead injected mouse. Bacteria is competent, in biological terms, meaning that cells can take up "naked" DNA from it's environment. Knowing that fact, when the heat-killed S-strain pneumoccus mixed with the live R-strain, the R-strain took in the DNA, therefore inheriting the deadly coating of the S-strain. So the R became S, and killed the mouse.
that it was very gay
To find out, he took a culture of these cells, heated the bacteria to kill them, and injected the heat-killed bacteria into the mice.
To find out, he took a culture of these cells, heated the bacteria to kill them, and injected the heat-killed bacteria into the mice.
S Strain ---> inject into mice ---> Mice Die R Strain ---> inject into mice ---> Mice Live Griffith was able to kill bacteria by heating them. He observed that heat-killed S Strain bacteria injected into mice did not kill them. When he S Strain (heat Killed) ---> Injected into mice ---> Mice Live S Strain ( heat Killed) + R Strain (Live) ---> Injected into mice ---> Mice Die
To find out, he took a culture of these cells, heated the bacteria to kill them, and injected the heat-killed bacteria into the mice.
What did griffith observe when he injected into mice a mixture of heat-killed disease-causing bacteria and live harmless bacteria?
t He then took the R strain (rough strain) and injected it into the mice and found that they did not contract the pneumonia illness and survived the insertion of the strain
The difference between "walking pneumonia" and "true pneumonia".
The scientist was Frederick Griffith, in 1928. Although he believed proteins were involved, it was actually the transfer of DNA. The harmless pneumonia bacteria acquired the DNA from the killed viruses, and became equally lethal.
the mice grew sick and died.(totally CORRECT, I got this out of a worksheet the teacher gave me so you can count on this answer... OH YES YOU'RE VERY WELCOME, ANYTIME)
Griffith discovered transformation. Transformation is what we would today describe as the motion of DNA from one cell to another. But in those days, it was not known that DNA was the genetic material. All that was known was that something caused transformation.S virulent strains of Streptococcus pneumoniae were injected into mice. The mice promptly perished from pneumonia due to the bacterial virulence. Second, mice had R nonvirulent strain of Streptococcus pneumoniae injected. The mice were fine afterwards due to the nonvirulence of the bacterium. Heat killed S virulent bacteria had no effect either. However something rather sinister happened when S virulent (heat killed) and R nonviruent were mixed in together and entered the mice.The S virulent were dead and could do nothing. But it appeared a transforming medium must have traversed from them to the R nonvirulent (live) strain. The R nonvirulent became S virulent and killed the mice ferociously. Something very odd had happened. A transforming principle. Transformation had been discovered.nicely put, but you missed some points.Fredrick Griffith was a bacteriologist who discovered transformation. Transformation is what we would today explain as the movement of DNA from one cell to another. But back in those days, DNA was not known as a genetic material; all they know was that something caused transformation. In his experiment, Griffith found that if the dangerous S bacteria strains of Streptococcus pneumonia (that he put in a capsule to stop the bodies defense systems) were injected into mice, then the mice quickly died from pneumonia because of the bacterial poisoning. The other mice that were infected with the R bacteria were fine. In order to see if the capsules were killing the mice, Griffith injected dead S bacteria in the mice, but that had no effect. So, afterwards, he injected the mice with heat-killed S bacteria, but that had no effect either. So now, Griffith knew that the capsule did not kill the bacteria. The purpose of the heat-killed bacteria was so they could no longer reproduce. However something pretty disturbing happened when the previously harmless heat-killed S bacteria and previously harmless R bacteria were mixed in together and injected into the mice, the mice died. Griffith, mystified, checked the blood of the dead mice and found that the harmless R bacteria had aqquierd capsules. So, in other words the harmless R bacteria had become the harmful S bacteria. Griffith had discovered what we now call "transformation".
The pathogenic DNA from the dead bacteria became active when combined with the DNA in the live bacteria. When injected into the mice, this reactivated DNA caused the disease and the mice died.