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A frameshift mutation will have the most serious effects.
A frameshift mutation is a type of mutation involving the insertion or deletion of a nucleotide in which the number of deleted base pairs is not divisible by three.
Divisible by three is important because the cell reads a gene in groups of three bases.
Each group of three bases corresponds to one of 20 different amino acids used to build a protein.
If a mutation disrupts this reading frame, then the entire DNA sequence following the mutation will be read incorrectly.

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5'- atg ctt aat gcg cca gtg tgc AA agg gcg - 3'?

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