A frameshift mutation will have the most serious effects.
A frameshift mutation is a type of mutation involving the insertion or deletion of a nucleotide in which the number of deleted base pairs is not divisible by three.
Divisible by three is important because the cell reads a gene in groups of three bases.
Each group of three bases corresponds to one of 20 different amino acids used to build a protein.
If a mutation disrupts this reading frame, then the entire DNA sequence following the mutation will be read incorrectly.
A frameshift mutation that alters the reading frame of a gene will typically have more evolutionary consequences compared to other types of mutations. This is because it can completely change the amino acid sequence of the resulting protein, leading to significant functional changes that may impact an organism's survival and reproduction.
A frameshift mutation, such as an insertion of one nucleotide, is most likely to produce a protein with one extra amino acid. This type of mutation shifts the reading frame of the genetic code, leading to a change in the entire sequence of amino acids after the mutation site.
A mutation that involves a single nucleotide is called a point mutation. This type of mutation can include substitutions, insertions, or deletions of a single nucleotide in the DNA sequence.
A point mutation, in which one nitrogen base in a codon is substituted for another, may have no effect on an organism. This is true if the base substitution does not change the amino acid that the codon represents, or if the mutation occurs in a non-critical location in the protein so that the protein's structure is not changed significantly and the protein is still able to function.
Chromosomal mutation
A frameshift mutation
There is no single type of mutation that causes Hemophilia A. It is not the type of mutation but rather the location of the mutation within the genetic code.
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The most common type of mutation is a point mutation, where a single nucleotide base is changed, inserted, or deleted in the DNA sequence. This can result in a different amino acid being incorporated into the protein during translation, leading to potential changes in the protein's function.
It is a mutation/
chromosomal mutation
A silent mutation
Hemophilia is a mutation of either of the genes that make factor VII or IX. Hemophilia A is a mutation of the F8 gene and Hemophilia B is the mutation of the F9 gene. Both of these mutations occur on the sex-linked X chromosome.
A frameshift mutation, such as an insertion of one nucleotide, is most likely to produce a protein with one extra amino acid. This type of mutation shifts the reading frame of the genetic code, leading to a change in the entire sequence of amino acids after the mutation site.
deletion mutation
A mutation that involves a single nucleotide is called a point mutation. This type of mutation can include substitutions, insertions, or deletions of a single nucleotide in the DNA sequence.
A frameshift mutation in the CARD15 gene
A one base left out mutation is called a deletion mutation. This type of mutation involves the loss of one or more nucleotides from a DNA sequence, which can lead to a frameshift mutation if not in multiples of three.