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What is the type of mutation that causes hemophilia?
There is no single type of mutation that causes Hemophilia A. It is not the type of mutation but rather the location of the mutation within the genetic code.
Is hemophilia a insertion mutation?
Maybe
Is hemophilia a defect?
Hemophilia is a genetic mutation of the sex-linked X chromosome.
What is a carrier for hemophilia?
A carrier for hemophilia is a female who carries the genetic mutation for hemophilia on one of her X chromosomes, but does not exhibit symptoms of the condition herself. Carriers can pass on the gene mutation to their children, resulting in hemophilia in male offspring. Testing can confirm carrier status.
Is hemophilia caused by inbreeding?
No, hemophilia is a genetic disorder caused by a mutation in the genes responsible for blood clotting, and it is not directly caused by inbreeding. Inbreeding can increase the likelihood of inheriting genetic disorders, including hemophilia, if the mutation is present in the family's gene pool.
Does frame shift mutation affect hemophilia?
Frame shift mutations that occur on the X chromosome and within the potion of code that controls the formation of clotting factors can cause hemophilia. Frame shift mutations are only one of many types of mutations that can cause the disorder. For hemophilia it's not so much the type of mutation but the location of the mutation within the genetic code.
Why are females less likely to get hemophilia?
Females are less likely to show the symptoms of hemophilia but in actuality are more likely to have the genetic mutation for hemophilia. The reason they are less likely to show the symptoms is the fact that hemophilia is the result of a mutation on the X chromosome. Since females have two X chromosomes they likely have a chromosome that is not mutated as well. With the mutation normally being a recessive trait, the normal X chromosome is usually expressed instead. Since males only have one X chromosome, if the mutation for hemophilia is present, it will be expressed. For the same reasons, the chances of a female having the mutation is greater (however still very small), simply because she has two X chromosomes.
Which chromosome contains the gene for hemophilia?
The X chromosome. That's why it's more common in males; females have 2 X chromosomes, but males only have 1. So if a woman has the hemophilia mutation on one of her chromosomes, she probably won't be affected by it.
What happens to the DNA that results Hemophilia A?
There are several different mutations that can cause hemophilia and there is no typical answer to this question. There are different segments of code on the X chromosome that is responsible for enabling production of Factors VIII & IX. A mutation anywhere within these areas can be responsible for hemophilia. The type of mutation as well as the location of the mutation in that code can influence the severity of hemophilia as well. Lets look at a reversal mutation that results in the creation of a stop codon (this type of mutation is often called a nonsense mutation) early on in the code sequence. The stop codon tells the machinery to stop production of the factor protein molecule at that point. In this case, the molecule would never actually be made. If we look instead at a point mutation resulting in simply an incorrect amino acid in that location (often called a missense mutation) half way through the code sequence, results can vary dramatically. The factor molecule will be made incorrectly, either not functioning for its purpose at all or simply doing a less than efficient job. I hope that helps some.
Is hemophilia visble in karyotype?
No. The X chromosome with the mutation will look no different than any other X chromosome. In order to see the mutation you would have to actually examine the base pairs and sequences. A single reversal, translation, deletion, or mutation of any kind within the specific segment of code can result in hemophilia. This will not result in an overall change in appearance of the chromosome.
Is hemophilia a hereditary disease or acquired from microorganisms?
Hemophilia is not acquired from microorganisms. Hemophilia is typically a genetic disorder that can either be inherited or result from a random mutation. In rare cases non genetic forms (that can not be inherited or passed on) of hemophilia can be acquired due to liver impairment, and certain medications.
Is hemophilia due to heredity?
Yes hemophilia is a inheerited bleeding dissorder. i read it from my medical book. hemophilia means blood love and can be passed down from mother to daughter. or in some cases mother to son. it is more common for it to passed to daughters. I hope this helped. :)
