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Explain why a woman carrying a gene for hemophlia can produce hemophilic sons when she is mated with a normal male?
A woman carrying a gene for hemophilia is typically a carrier with one X chromosome carrying the hemophilia gene and one X chromosome carrying the normal gene. When she is mated with a normal male who has one X chromosome and one Y chromosome, there is a 50% chance that the son will inherit the X chromosome carrying the hemophilia gene from the mother. Since males have only one X chromosome, if they inherit the hemophilia gene, they will express the disorder.
Why is hemophilia rarely expressed in females?
Because hemophilia is a disease linked to a recessive gene on the X-chromosome, females have another X-chromosome to block out the diseased one. However, males have only one X-chromosome, so they are more often subject to hemophilia.
What chromosomes has been determined to carry this gene in hemophilia?
the X chromosome
If you know a woman has hemophilia what can you infer about her parents genetype?
Her father has to have hemophilia as well, and the mother is a carrier or also has hemophilia. So if we pretend that the hemophilia gene is "x", you need to have "xx" to have hemophilia. The father must have the genotype "Yx" and the mother has the have "Xx" or "xx".
Why is hemophilia considered to be a sex link trait?
Because the gene that causes hemophilia is located on the X chromosome, so it will occur in males more frequently than in females.
Is hemophilia a chromosome abnormality?
Hemophilia is not classified as a chromosome abnormality; rather, it is a genetic disorder caused by mutations in specific genes responsible for blood clotting factors. Most commonly, hemophilia A is linked to mutations in the F8 gene, and hemophilia B is associated with the F9 gene. These genes are located on the X chromosome, which is why hemophilia predominantly affects males, while females can be carriers. Thus, while it involves genetic factors, hemophilia itself is not due to a chromosomal abnormality.
What gene or chromosome is mutated in the hemophilia disorder?
Hemophilia is most often caused by mutations in the F8 gene, located on the X chromosome. This gene provides instructions for making a protein called factor VIII, which is essential for blood clotting. Mutations in the F8 gene can result in reduced or absent levels of factor VIII, leading to the characteristic bleeding problems seen in hemophilia.
Which chromosome contains the sex gene?
chromosome 1 chromosome 1
A woman is a carrier for hemophilia what is the chances for sons with hemophilia if the father does not have hemophilia?
There are no hard answers to this, it depends strictly on luck. The statistics are though not very good for their children. Statisically the couple have a chance of having a normal son, a daughter that is a carrier for hemophilia, a daughter with hemophilia and a son with hemophia.
A recessive gene located on the X chromosome is the cause of hemophilia in affected individuals. Males are more likely to have hemophilia than females because?
Males only have one copy of the X chromosome
A baby daughter is born with hemophilia what is the genotype of her father?
Hemophilia is an X-linked recessive disorder, meaning the gene responsible for the condition is located on the X chromosome. Since the baby daughter has hemophilia, she must have inherited one affected X chromosome from her father. Therefore, the father must have the genotype X^hY, where X^h represents the X chromosome carrying the hemophilia gene, indicating that he is affected by the condition.
A woman is a carrier for hemophilia what are the chances for sons with hemophilia if the father does not have hemophilia?
Since the gene for Hemophilia is carried on the X chromosome and males pass only their Y chromosome onto their sons, no their sons should not have hemophilia. Of course all daughters of a male with hemophilia will be carriers of the mutation since they with receive his X chromosome, not the Y.
