Because hemophilia is a disease linked to a recessive gene on the X-chromosome, females have another X-chromosome to block out the diseased one. However, males have only one X-chromosome, so they are more often subject to hemophilia.
XhXh - with hemophilia XhXH- carrier of hemophilia
Males only have one copy of the X chromosome
Hemophilia normally refers to a genetic disorder that can be either inherited or the result of a spontaneous mutation. Since the genetic form of hemophilia is linked to a mutation on the X chromosome, males typically show the full symptoms while females with the mutation typically have somewhat mitigated symptoms or none at all. While the majority of the cases of genetic hemophilia are inherited, meaning that the genes were passed down from the the parents, approximately 1/3 of the cases are spontaneous mutations. The mutation occurs at conception, meaning that all genetic forms basically take effect at birth. Acquired hemophilia is a result of some other influence such as liver damage or specific medications. This form of hemophilia is neither inherited nor genetic. In short, technically anyone can get hemophilia. Genetic hemophilia is present at birth, and it tends to impact the health of males more than females, but can affect females too.
Exceptions are always there e.g hemophilia and many bleeding disorders don't affect females.
This is due to the fact that females have two X chromosomes while males have only one, lacking a 'back up' copy for the defective gene the defective gene becomes manifest more easily in males. Because females have two X chromosomes and because hemophilia is rare, the chance of a female having two defective copies of the gene is very low, thus females are almost exclusively asymptomatic carriers of the disorder. It is very rare for a female to have hemophilia
Females are less likely to show the symptoms of hemophilia but in actuality are more likely to have the genetic mutation for hemophilia. The reason they are less likely to show the symptoms is the fact that hemophilia is the result of a mutation on the X chromosome. Since females have two X chromosomes they likely have a chromosome that is not mutated as well. With the mutation normally being a recessive trait, the normal X chromosome is usually expressed instead. Since males only have one X chromosome, if the mutation for hemophilia is present, it will be expressed. For the same reasons, the chances of a female having the mutation is greater (however still very small), simply because she has two X chromosomes.
females have 2 alleles for hemophilia, (X^hX^H) and (X^hX^h) if H is the normal allele and h is the recessive allele for hemophilia
The genes associated with Hemophilia A and B are located on the X chromosome, which is one of the 2 sex chromosomes. For males, who have only 1 X chromosome, 1 altered copy of the gene in each cell is sufficient to cause hemophilia. In females, who have 2 X chromosomes, a mutation would have to occur in both copies of the gene to cause hemophilia. Since it is unlikely that females will have 2 altered copies of this gene it is therefor very rare for females to have hemophilia.
females have xand males dont
Yes females can have hemophilia. Although very rare it has been recorded. A female can get hemophilia if her mother is a carrier and her father has it. Like I said, It doesn't happen often but is possible.
The genes associated with Hemophilia A and B are located on the X chromosome, which is one of the 2 sex chromosomes. For males, who have only 1 X chromosome, 1 altered copy of the gene in each cell is sufficient to cause hemophilia. In females, who have 2 X chromosomes, a mutation would have to occur in both copies of the gene to cause hemophilia. Since it is unlikely that females will have 2 altered copies of this gene it is therefor very rare for females to have hemophilia.
Yes. Hemophilia is sex-linked, and is much more common in males than in females, but it is not impossible for a girl to have hemophilia.
XhXh - with hemophilia XhXH- carrier of hemophilia
cus i say so ahahahahah
Because the gene that causes hemophilia is located on the X chromosome, so it will occur in males more frequently than in females.
Because males have the chromosome XY. And Hemophilia attacks the X chromosomes, so if the disorder gets to the X chromosome of the male, it doesnt have another X chromosome to back it up like females do.(XX)
While the condition affects the males, it is CARRIED by the females, who do not suffer the effects of hemophilia, and can pass the disorder to THEIR female offspring.