Hershey and Chase chose to use viruses in their experiments because viruses are simple and can easily infect and replicate within host cells, making them ideal for studying the process of genetic material transfer.
Friedrich Miescher performed experiments in the lab at the University of Tubingen in 1868. He experimented with the chemical composition of leukocytes, and these experiments led to the discovery of DNA.
They found that all of the viral DNA and little of the protein had entered E. coli cells. Then they concluded that DNA is the hereditary molecule in viruses.
The scientists Alfred Hershey and Martha Chase conducted a series of experiments at the Carnegie Institute of Washington in 1952, and concluded that the genetic material of a bacteriophage was DNA.
The Avery and Hershey-Chase Experiments • Alfred Hershey and Martha Chase provided the final experimental evidence that pointed to DNA as the hereditary material the team studied viruses that infect bacteria -the structure of these viruses is very simple: a core of DNA surrounded by a coat of protein -the viruses attach themselves to the surface of bacteria cells and inject their genes into the interior • the infected bacterial cell is then forced to make hundreds of copies of new viruses, which then burst out of the cell to infect new cells. • Hershey and Chase used radioactive isotopes to "label" or tag the DNA and the protein of the viruses -some viruses were grown so that their DNA contained radioactive phosporous (32P) -other viruses were grown so that their protein coats contained radioactive sulfur (35S) After the labeled viruses were allowed to infect bacteria, only the viruses with 32 P had labeled tracer in their interior • The conclusion was that the genes that viruses use to specify new viruses are made of DNA and not protein
In their experiments, Hershey and Chase injected chemical tracers that resembled proteins and DNA into a type of rapidly reproducing virus called T2. They then tracked the course of the tracers as they made their way through reproduction and found that the tracers that resembled DNA were much more likely than the tracers that resembled proteins to be found in future generations of the cells. Hershey and Chase concluded that DNA, and not protein, was associated with genetic material.
Markers :)
Markers-Nova Net
Bacteriophage
Hershey and Chase
DNA controls heredity, not proteins.
Friedrich Miescher performed experiments in the lab at the University of Tubingen in 1868. He experimented with the chemical composition of leukocytes, and these experiments led to the discovery of DNA.
Griffith, Avery, Hershey, and Chase
According to my bio book, I think it's Alfred Hershey and Martha Chase, in the HERSHEY-CHASE experiment.
The genetic mateial is made of DNA and not of proteins
They found that all of the viral DNA and little of the protein had entered E. coli cells. Then they concluded that DNA is the hereditary molecule in viruses.
they studied viruses and nonliving particles smaller than a cell that may infect living organisms.
Hershey and Chase used radioactive sulfur-35 to tag phage proteins and radioactive phosphorus-32 to tag phage DNA in their experiments on bacteriophages.