The chloride ions have made the mucus more concentrated of the ions. The water moves from a high concentration of water in the cells to a low concentration of water which is in the mucus; in order to dilute the more concentrated solution. It travels by osmosis through a partially permeable membrane.
because the cell surface grows because is makes the mucus thicker
The defective channel causes a build up of chlorine ions in the airways cells. This higher concerntration of chlorine causes water to enter ther cell via osmosis. The water is removed from the mucus in the airway and because the chloride channel is no longer letting chlorine out the water remains in the cell and not in the mucus.
Cystic Fibrosis
The cells that makes mucus are called goblet cells. These are glandular simple columnar epithelial cells that secrete gel forming mucins, which are the major component of mucus.
You may be thinking of the sublingual gland. But there are many mucus secreting cells embedded in the epithelium of various tissues (such as intestinal tract, female reproductive tract, etc.)
The Wine glass shaped cells that secrete mucus are called "goblet cells". These are simple columnar epithelial cells found scattered among the epithelial linings of intestine and respiratory tract.
The defective channel causes a build up of chlorine ions in the airways cells. This higher concerntration of chlorine causes water to enter ther cell via osmosis. The water is removed from the mucus in the airway and because the chloride channel is no longer letting chlorine out the water remains in the cell and not in the mucus.
The faulty gene causes the misfolding of a protein called the Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR is responsible for the movement of chloride and sodium ions into and out of cells. The lack of salt and water on the surface of the cells causes the mucus to become extremely thick and sticky which builds up in and clogs organs.
the gene that codes for an important cell membrane protein called cystic fibrosis transmembrane conductance regulator CFTR which acts as a chloride channel to transport chloride ions in and out of the epithelial cells in GIT and respiratory tract and also cells of sweat glands .
Cystic Fibrosis
The cells that makes mucus are called goblet cells. These are glandular simple columnar epithelial cells that secrete gel forming mucins, which are the major component of mucus.
The cells that makes mucus are called goblet cells. These are glandular simple columnar epithelial cells that secrete gel forming mucins, which are the major component of mucus.
What about blood-tinged mucus that follows a normal bowel movement?
Goblet cells stomach
mucus causes green saliva>
Infection.
Ploysinusitis is the simultaneous inflammation of multiple sinuses. What causes this is that mucus gland gets blocked, but the gland keeps making mucus and cannot drain out. The mucus will then stretch the gland and creating a mucus filled cyst.
A gene (CFTR) makes a protein that controls the movement of salt and water in and out of your body's cells. In people who have CF, the gene makes a protein that doesn't work well. This causes thick, sticky mucus and very salty sweat.CFTR gene provides the information needed to transport sodium and chloride ions across the cell membrane. This in turn controls the flow of water in mucus, sweat, tears, saliva, and digestive enzymes.Cystic fibrosis (CF) is a genetic disorder (autosomal recessive) caused by mutation in the gene that codes for the protein (cystic fibrosis transmembrane conductance regulator) CFTR. This protein regulates the making of sweat, digestive fluids, and mucus. In absence of this protein there will be impairment or abnormal transport of ions (Na or Cl) across the epithelium.