Yes. A synapse by definition is the space (gap) between one neurons terminal buton and another neurons dendrites. So, the neuron with the terminal buton end is known as the pre-synaptic neuron and the neuron after the synapse is known as the post-synaptic neuron.
There's not necessarily any difference between the two, the difference is simply which part of a neuron is at the beginning (pre-) and the end (post-) of a synapse.
The pre-synaptic neuron is the neuron which comes toa synapse, and the part of that neuron which comes to the synapse is an axon terminal (or axon bouton or button); the post-synaptic neuron is the neuron which comes from a synapse, and the part of that neuron which comes from the synapse is a dendrite, or a dendritic spine.
Presynaptic neuron sends postsynaptic receives
Divergent
a neuron from the axon terminal of which an electrical impulse is transmitted across a synaptic cleft to the cell body or one or more dendrites of a postsynaptic neuron by the release of a chemical neurotransmitter.
The nervous system would not work if ion channels were blocked. It would be like parking your car on a hose and trying to get water out of the hose.
Most neurons are at a negative membrane potential so when a ligand operated channel opens there is an inflow of positively charged ions, mostly but not exclusively sodium. If the neuron cell membrane has voltage-operated channels (the textbook example) then the inflow of positive ions can open the voltage-operated channels causing an even greater flow of positive ions into the neuron. This positive feed arrangement can lead to the neuron transitioning from negative to respect to outside of the cell to positive (overshoot). Since the voltage-operated channels inactive and also due to the potassium specific channels the cell is returned it's pre-action potential negative level (close to potassium's equilibrium potential).
Presynaptic neuron sends postsynaptic receives
endocannabinoids
Divergent
Every time neurotransmitter is released from the presynaptic neuron it generates an excitatory post synaptic potential(EPSP) in the postsynaptic neuron. When the EPSP is greater than the threshold for excitation an action potential is generated.
Neurotransmitters are released in response to stimulation. They alter the physiology of the postsynaptic cell. They are synthesized by a presynaptic neuron. They bind to specific receptors on the postsynaptic cell.
Let's picture a presynaptic neuron, a synaptic cleft, and a postsynaptic neuron. An action potential reaches the terminal of a presynaptic neurone and triggers an opening of Ca ions enters into the depolarized terminal. This influx of Ca ions causes the presynaptic vesicles to fuse with the presynaptic membrane. This releases the neurotransmitters into the synaptic cleft. The neurotransmitters diffuse through the synaptic cleft and bind to specific postsynaptic membrane receptors. This binding changes the receptors into a ion channel that allows cations like Na to enter into the postsynaptic neuron. As Na enters the postsynaptic membrane, it begins to depolarize and an action potential is generated.
chemical synapse
a neuron from the axon terminal of which an electrical impulse is transmitted across a synaptic cleft to the cell body or one or more dendrites of a postsynaptic neuron by the release of a chemical neurotransmitter.
spatial summation
The space between neurons is called the synaptic cleft. It is where neurotransmitters are released by the presynaptic neuron, travel across the cleft, and bind to receptors on the postsynaptic neuron to transmit chemical messages.
Receptors for the various neurotransmitters are located on both the presynaptic and postsynaptic nerve terminals of the neuron.
When the action potential reaches the button(axon terminal) of the presynaptic neuron the depolarization causes voltage gated calcium channels to open increasing intracellular calcium content. This causes synaptic vesicles to fuse to the membrane and release neurotransmitters that bind to the post synaptic neuron and create a chemical action potential.