thymine, cytosine, thymine, guanine, adenine
*HINT*
"A" goes with "T" always
and "C" goes with "G" always
Hydrogen bonds hold together the nucleotide bases in a DNA molecule. There are specific base pairings: adenine (A) pairs with thymine (T) and cytosine (C) pairs with guanine (G), connected by hydrogen bonds. These bonds contribute to the stability and structure of the DNA molecule.
ATP (adenosine triphosphate) is made up of carbon, hydrogen, oxygen, nitrogen, and phosphorus atoms. These atoms are organized in specific arrangements to form the nucleotide molecule that serves as the primary energy carrier in cells.
nucleotides that are arranged in a specific sequence. This sequence determines the genetic information encoded in the RNA molecule, which can be involved in various cellular functions such as protein synthesis, regulation, and signaling.
Transfer RNA (tRNA) is the molecule responsible for picking up amino acids and bringing them to the ribosome during protein synthesis. Each tRNA molecule carries a specific amino acid and has an anticodon that pairs with the complementary codon on the messenger RNA (mRNA) being translated.
The relationship between nucleotide sequence and amino acid sequence is called the genetic code.- - -In those segments of DNA that carry information about proteins, the sequence of the nucleotides determines the sequence of amino acids in a polypeptide chain (one chain of a protein).A group of three consecutive nucleotides codes for (represents) one amino acid. This group is called a codon.The different amino acids are coded for by different codons. What each of the 64 codons stands for is the genetic code.Three of the codons mean STOP; each of the 61 others stands for one of the 20 amino acids. In addition, one of the codons does double duty: it means START when it appears in a particular position.The coding sections of DNA are called genes. Some genes code for RNA (such as transfer and ribosomal RNA); polypeptide chains are coded for by other genes, or, more specifically, exons of those genes. The exons are often separated by introns, which, although consisting of a sequence of nucleotides, do not code for amino acids.The idea that nucleotide sequence (often referred to as base sequence) might code for amino acid sequence followed the proposal of the double-helix structure for DNA in 1953.In 1958 Francis Crick gave the name sequence hypothesisto the idea that the nucleotide sequence corresponded to the sequence of amino acids in the chain to be synthesized. (For some reason this name is not well known now, and is often confused with Crick's term "central dogma", which, as Crick used it, denotes a different concept.)In 1961 there were two important breakthroughs. Crick and Sydney Brenner showed that the code consisted of "triplets" (Brenner coined the word codon the following year), and Marshall Nirenberg and Heinrich Matthaei developed a technique for working out the code (in its messenger RNA version).By 1966 all the 64 possible codons had been worked out.
Molecular bases
A mutation in a DNA nucleotide sequence would be more harmful than a mutation in a mRNA nucleotide sequence because it could cause the synthesis of multiple nonfunctional proteins in comparison to a mutation in a mRNA nucleotide sequence that would be less harmful because it would result in a few nonfunctional proteins.
They are attached to a deoxyribose sugar.
The terminator in mRNA synthesis is a specific DNA sequence that signals the end of transcription. When the RNA polymerase reaches the terminator sequence, it stops transcribing the mRNA molecule, releasing it from the DNA template.
The genetic code is determined by the specific sequence of four nucleotide bases that make up DNA. The bases are guanine, adenine, thymine, and cytosine.
Yes, DNA carries the instructions for the correct sequence of nucleic acids in a protein. These instructions are encoded in the DNA molecule as a specific sequence of nucleotide bases (adenine, thymine, cytosine, and guanine). Through a process called transcription, the DNA sequence is transcribed into a messenger RNA (mRNA) molecule, which is then translated into a specific sequence of amino acids to form a protein.
Single nucleotide resolution refers to the ability to identify a specific nucleotide base at a particular position within a DNA or RNA molecule. This level of resolution allows for precise mapping and analysis of genetic information, enabling researchers to investigate specific mutations, variations, or modifications at the individual nucleotide level. Techniques such as next-generation sequencing can provide single nucleotide resolution by accurately determining the nucleotide sequence at each position.
They are attached to a deoxyribose sugar.
tRNA
The nucleotide sequence in DNA is determined by the sequence of the nitrogenous bases (adenine, thymine, cytosine, and guanine) along the DNA strand. These bases pair up in specific ways: adenine with thymine and cytosine with guanine. The order in which these bases are arranged along the DNA molecule determines the genetic information encoded within the DNA.
Point mutation and it can be effective or silent depend upon at the site of codon
A cluster of three nucleotides is called a 'codon' - However, the term is only really used to refer to refer to a 3 nucleotide sequence on an mRNA molecule. Codons provide a means by which charged tRNA molecules can specifically add amino acids to a growing polypeptide chain. tRNA molecules have the complementary 3 nucleotide sequence (anticodon) that allow the specific recognition.