The grignard might form but the reagent prefers to act as a base and will undergo hydrolysis and be destroyerd before isolation in reaction with any compound containing OH groups
You first must add on a carbon....lets do it.... One could do this by the Grignard.......but I am going to show you a more cleaver way !!!!!!! Treat propanal with K2Cr2O7 , and H3O+.....to get the carboxy acid.....then treat it with SOCl2.......you now have propanoyl chloride. Now,,,,,,for the master move.....treat with ( CH3)2CuLi in ether. .....then reduce with NaBH4 in methanol.....and you got it. Dr. Jim Romano CEO Orgoman.com NYU Class of 1991
The beauty of grignard reagents is their relative ease of production, in simple terms just take an alkyl halide add magnesium and stir to get RMgX which can then be reacted further. The difficulty in using calcium is that the metal itself is less reactive and calcium organometallics are relativelly unstable. Calcium organohalides are also more salt-like and are not as soluble as their Mg counterpart. This whole area is not that well understood, the mechanism of production of grignards is unclear. Certainly alkylcalcium halides are known but they are difficult to prepare and are described as extremely unrreactive.
You must initially convert it into benzene then heat it with Zn dust. And add CH3-Cl+anhydrous AlCl3 followed by hot concentrated KMnO4.
The beauty of grignard reagents is their relative ease of production, in simple terms just take an alkyl halide add magnesium and stir to get RMgX which can then be reacted further.The difficulty in using calcium is that the metal itself is less reactive and calcium organometallics are relativelly unstable. Calcium organohalides are also more salt-like and are not as soluble as their Mg counterpart.This whole area is not that well understood, the mechanism of production of grignards is unclear. Certainly alkylcalcium halides are known but they are difficult to prepare and are described as extremely unrreactive.If you have access to a library then see:-Volume 252, Issues 15-17, August 2008, Pages 1516-1531Recent Advances in Organometallic Chemistry: 2008ReviewHeavy Grignard reagents-Synthesis and reactivity of organocalcium compounds by Matthias Westerhausen
To convert ethyl chloride into tetraethyl lead, you would first need to convert ethyl chloride into ethyl Grignard reagent using magnesium as the catalyst. This intermediate compound can then be reacted with lead chloride to form tetraethyl lead. It's important to note that this process requires careful handling due to the toxicity of tetraethyl lead.
You first must add on a carbon....lets do it.... One could do this by the Grignard.......but I am going to show you a more cleaver way !!!!!!! Treat propanal with K2Cr2O7 , and H3O+.....to get the carboxy acid.....then treat it with SOCl2.......you now have propanoyl chloride. Now,,,,,,for the master move.....treat with ( CH3)2CuLi in ether. .....then reduce with NaBH4 in methanol.....and you got it. Dr. Jim Romano CEO Orgoman.com NYU Class of 1991
The beauty of grignard reagents is their relative ease of production, in simple terms just take an alkyl halide add magnesium and stir to get RMgX which can then be reacted further. The difficulty in using calcium is that the metal itself is less reactive and calcium organometallics are relativelly unstable. Calcium organohalides are also more salt-like and are not as soluble as their Mg counterpart. This whole area is not that well understood, the mechanism of production of grignards is unclear. Certainly alkylcalcium halides are known but they are difficult to prepare and are described as extremely unrreactive.
You must initially convert it into benzene then heat it with Zn dust. And add CH3-Cl+anhydrous AlCl3 followed by hot concentrated KMnO4.
The beauty of grignard reagents is their relative ease of production, in simple terms just take an alkyl halide add magnesium and stir to get RMgX which can then be reacted further.The difficulty in using calcium is that the metal itself is less reactive and calcium organometallics are relativelly unstable. Calcium organohalides are also more salt-like and are not as soluble as their Mg counterpart.This whole area is not that well understood, the mechanism of production of grignards is unclear. Certainly alkylcalcium halides are known but they are difficult to prepare and are described as extremely unrreactive.If you have access to a library then see:-Volume 252, Issues 15-17, August 2008, Pages 1516-1531Recent Advances in Organometallic Chemistry: 2008ReviewHeavy Grignard reagents-Synthesis and reactivity of organocalcium compounds by Matthias Westerhausen
To convert ethyl chloride into tetraethyl lead, you would first need to convert ethyl chloride into ethyl Grignard reagent using magnesium as the catalyst. This intermediate compound can then be reacted with lead chloride to form tetraethyl lead. It's important to note that this process requires careful handling due to the toxicity of tetraethyl lead.
How would you have reacted if you were Ms. Allen? Explain why
How would you have reacted if you were Ms. Allen? Explain why
Susan reacted badly to the medication she was subscribed by her doctor.
it reacted that way do to chemical reactions.
"Reacted" is a verb in the past tense form. It is not a participle or a gerund.
The word reacted is a verb. It is the past tense of the verb react.
the congress reacted to the kkk's terror by passing the radical reconstrustion