By addition of 10% ethanolic KOH, water and HCl
SAPONIFICATION
I assume you mean ethanol + KOH? if so, in order to prevent co-precipitation of piperine and the resin acids, dilute ethanolic KOH is added to the concentrated extract to keep acidic materials in solution as their potassium salts (acid/base rxn occurs). basically it keeps impurities in solution, while piperine precipitates out.
Acidic hydrolysis: hydrolysis in an acid solution (pH under 7) Basic hydrolysis: hydrolysis in a basic solution (pH above 7)
hydrolysis
in the hydrolysis of sucrose a catalyst such as sucrase must be applied
SAPONIFICATION
salts of strong acid and strong base do not undergo hydrolysis
the reaction in which cation or anions of salts reacts with water to produce acid or base is called salt hydrolysis.
I assume you mean ethanol + KOH? if so, in order to prevent co-precipitation of piperine and the resin acids, dilute ethanolic KOH is added to the concentrated extract to keep acidic materials in solution as their potassium salts (acid/base rxn occurs). basically it keeps impurities in solution, while piperine precipitates out.
If the base hydrolysis mechanism is important, an electron withdrawing group can be attached to the prodrug. If the acid hydrolysis mechanism is important, an electron donating group can be attacked to the prodrug.
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The most important component is piperine.
An acid-base reaction that leaves no excess H+ or OH-
According to a research conducted at Department of Pharmacy King's College London piperine helps in frequent repigmentaion and its results lasts longer than many other treatments. In this research, researchers first analyzed the herbs and plants used in herbal vitiligo recipes to see if any of the ingredients could stimulate pigment cell multiplication in vitro. You can use herbal recipes which have piperine as its ingredient. Piperine is derived from black pepper so another source of piperine is black pepper. For more information on vitiligo research visit: http://www.vitiligoguide.com/vitiligo-research/
Acidic hydrolysis: hydrolysis in an acid solution (pH under 7) Basic hydrolysis: hydrolysis in a basic solution (pH above 7)
Black pepper contain piperine.
hydrolysis