They bind in the active site.
A ligase enzyme catalyzes the joining of two molecules by forming a chemical bond. This enzyme brings reactants closer together to facilitate the formation of the bond.
A noncompetitive inhibitor is a substance that can bind to the enzyme at a location other than the active site, altering the enzyme's shape and reducing its activity. This type of inhibition does not compete with the substrate for binding to the enzyme.
Competitive inhibitors bind to the active site of an enzyme, preventing the substrate from binding. Noncompetitive inhibitors bind to a site other than the active site, changing the shape of the enzyme and preventing substrate binding. Uncompetitive inhibitors bind only to the enzyme-substrate complex, preventing catalysis.
Enzyme inhibitors are molecules that bind to enzymes and decrease their activity. The binding of an inhibitor can stop a substrate from entering the enzyme's active site and/or hinder the enzyme from catalyzing its reaction. Inhibitor binding is either reversible or irreversible. Irreversible inhibitors usually react with the enzyme and change it chemically. These inhibitors modify key amino acid residues needed for enzymatic activity. In contrast, reversible inhibitors bind non-covalently and different types of inhibition are produced depending on whether these inhibitors bind the enzyme, the enzyme-substrate complex, or both.
Substrates in an enzymatic reaction are the reactants. They are the molecules that are acted upon by the enzyme to produce the products of the reaction.
Substrates
The region where reactants bind to an enzyme during a biochemical reaction is called the active site. It is a specific region on the enzyme where the substrate binds, forming an enzyme-substrate complex that leads to the catalysis of the reaction.
the cell membrane
The structure is important because each enzyme's shapes allows only certain reactants to bind the enzyme.
Reactants. "Substrate" is another possibility.
The reactants of enzyme-catalyzed reactions are known as substrates. Substrates bind to the active site of an enzyme, where the reaction takes place. Enzymes help lower the activation energy required for the reaction to occur.
substrateSubstrates.substrate
The activation site of an enzyme can only bind to a specific substrate.
Noncompetitive inhibitors bind to a site on the enzyme that is not the active site.
separate-restriction endonucleasis bind-ligases
The substrate is the molecule affected by the enzyme.
Uncompetitive inhibitors bind to the enzyme at a different site than the active site.