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Over time, the sodium hydroxide will react with the smidges of carbon dioxide in air to produce sodium carbonate, the white, crusty powder that you find around the rim of plastic capped stock bottles (for example). This powder will either prevent the ground glass stopper from sealing properly and exposing the contents to more air, or will in fact cement the ground glass stopper in the bottle, and make it impossible to remove.

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Q: Why is it not advisable to use a ground glass stopper for a reagent bottle containing sodium hydroxide solution?
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