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How do you convert chlorhexidine solution 2 percent in to chlorhexidine gel 2 percent?
Chlorhexidine (CH) comes in three molecular entities: CH Gluconate, Acetate or Hydrochloride salts. Historically, CH gluconate (CHG) has been the most popular form due to ease of use. CHG comes as a 20% w/v solution. A simple 1 in 10 dilution gives your 2% w/v solution. CH mode of action is a cationic reaction with bacterial cell wall. Therefore, your gel excipients has either to be neutral or cationic as well. There are numerous books on pharmaceutical excipients and jellyfying agents. But keep in mind that the task of creating a gel is not an easy one as you will need to demonstrate In-Vitro efficacy as well as In-Vivo safety (irritation, sensitization,...) and efficacy (capacity to actually redice number of bacterias). I.E. on living human skin. If you are in USA, refer to TFM (Docket 75N-183H) if you are in Canada, refer to Human - Use Antiseptic Drugs. http:/www.hc-sc.gc.ca/dhp-mps/alt_formats/hpfb-dgpsa/pdf/prodpharma/draft_ebauche_antiseptic_guide_ld-eng.pdf
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Preparation of 1 percent agarose gel or How to prepare 1 percent agarose gel?
Check the answer for How do you make an electrophoresis gel?
What is the solvent in cytoplasm?
Cytosol which is composed of about 90% water and may be in the form of a solution or gel. Solution is non viscous state while gel is in viscous state. Peripheral parts of cells are often like a gel. Cytosol is a solution containing all the fundamental bio molecules of life.
Is jello a solution?
Jello is not a solution; it is a colloid gel of small cells of a solution within a continuous but porous phase of gelatin.
What is a difference between 2 percent and 3 percent agarose gel?
The main difference between a 2% and a 3% agarose gel is the concentration of agarose in the gel. A 3% agarose gel will have a higher agarose concentration, resulting in a higher resolving power for separating larger DNA fragments compared to a 2% agarose gel. However, a higher percentage agarose gel may also have a tighter mesh size, making it harder for larger DNA fragments to migrate through the gel.
Why is there a need to submerge the agarose gel into a tank of salt solution?
Submerging the agarose gel in a tank of salt solution helps to create an electrically conductive environment for electrophoresis to occur. The salt solution allows for the transfer of electric current through the gel, which is necessary for DNA or protein molecules to migrate through the gel and separate based on size or charge.
What is Synerheal Gel Debridement Ointment?
Introducing Synerheal Gel Debridement Ointment, a cutting-edge solution for comprehensive wound care
Is jelly a solution or a suspension or colloid?
Jelly is a gel (liquid-solid colloid).
What are the materials necessary for the gel apparatus?
To set up a gel electrophoresis apparatus, you will need a gel casting tray, gel comb, gel tank, gel tank lid, power supply, buffer solution, gel image documentation system, and agarose powder for making the gel. Additionally, you will need the DNA samples to be analyzed and loading dye to facilitate sample loading onto the gel.
How do you make sodium silicate solution?
To make sodium silicate solution, mix silica gel with sodium hydroxide in water. The ratio of silica gel to sodium hydroxide can vary depending on the desired concentration of the solution. Heat the mixture until the silica gel dissolves to form a clear solution.
What is the most effective blistering solution for treating burns?
The most effective blistering solution for treating burns is aloe vera gel.
Where does gel lie on the pH scale?
Gel does not have a pH level, as it is a physical substance and not a chemical solution. However, certain gels may contain ingredients that can affect pH levels if they are in a liquid form.
What is the function of buffer in the gel electrophoresis?
TBE buffer in gel electrophoresis is used to maintain pH of te solution and prevents the denaturation of smale fragments of DNA.
