Yes; here are a few definitions of it to show you:
As you can see, 'unimportant matters', 'childish manner', which often has neg connatations, 'foolish', 'irrelavant' etc.
Remarkable
dainty
you understand the connotation of the word compared to the original word.
Important, meaningful are near synonyms of significant.
The antonym of laugh is cry.
a synonym for prattle is talk
The word smelly has a negative connotation. A synonym with a positive connotation might be fragrant.
The synonyms for fastidious can include meticulous, exacting, or scrupulous. Words with a negative connotation are fussy or finicky.
If we're talking about an alternative synonym to the word picky that has no negative connotations, I would go with, 'Selective'.
Remarkable
Sometimes in this society it is used as a synonym for being thin, nd in that sense it can do, but when spoken of as the actual psychological illness, i wouldn't say it does.
dainty
To revel is anotherverb commonly used interchangeably with gloat, but it does not have as much of a negative connotation. One could also use to exult.
Some choices: foolish, idiotic, fatuous, puerile
you understand the connotation of the word compared to the original word.
Important, meaningful are near synonyms of significant.
I am not entirely sure as to whether you mean a positive synonym for "screeched", or whether the word itself has any positive connotations. A positive connotation for the word "screeched" could be the fact that although it is a harsh and displeasing noise, it is often used in conjunction with excitement. For example: "Wow!" she screeched, suggests that she is pleased, or incredibly surprised, and therefor is shrieking to express the above emotions. A synonym for "screeched" I rather like is "caterwauled".