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Resting membrane potential is determined by K+ concentration gradient and cell's resting permeability to K+, N+, and Cl-.

Gated channels control ion permeability. Three types of gated channels are mechanically gated, chemical gated, voltage gated. Threshold voltage varies from one channel type to another.

The Goldmann- Hodgkins-Katz Equation predicts membrane potential using multiple ions

The resting potential

Because the plasma membrane is highly permeable to potassium ions, the resting potential is fairly close to -90mV, the equilibrium potential for K+

Although the electrochemical gradient for sodium ions is very large, the membrane's permeability to these ions is very low. Consequently, Na+ has only a small effect on the normal resting potential, making it just slightly less negative than it would be otherwise.

The sodium-potassium exchange pump ejects 3 Na+ ions for every 2 K+ ions that it brings into the cell. It thus serves to stabilize the resting potential when the ratio of Na+ entry to K+ loss through passive channels is 3:2.

At the normal resting potential, these passive and active mechanisms are in balance. The resting potential varies widely with the type of cell. A typical neuron has a resting potential of approx -70mV

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Do all cells have a resting potential of -70mV?

No, not all cells have a resting potential of -70mV. The resting potential of a cell can vary depending on the type of cell and its function. However, many excitable cells, such as neurons, have a resting potential close to -70mV.


Does all body cells exhibit a resting membrane potential in their resting state therefore making all cells polarized?

In resting state, all body cells exhibit a resting membrane potential that typically ranges from -50 to -100 millivolts, depending on cell type. For this reason , all cells are said to be polarized.


What ion determines the resting membrane potential of nerve and muscle?

The potassium ion (K+) plays a major role in determining the resting membrane potential of nerve and muscle cells. This is because these cells have a higher permeability to potassium ions than other ions, such as sodium ions. As a result, the movement of potassium ions out of the cell through potassium leak channels leads to the establishment and maintenance of the negative resting membrane potential.


When the cardiac cells are in resting and negatively charged state this is known as?

When cardiac cells are in a resting and negatively charged state, this is known as the resting membrane potential. This resting state allows the cells to be ready to receive and transmit electrical signals for proper heart function.


What is resting potential?

A rest potential is the potential difference between two sides of the membrane of nerve cells when the cell is not conducting an impulse. =)


What accounts for the resting membrane potential seen in unstimulated nerve and muscle cells?

Sodium-potassium pump


What is the inside charge of a nerve at its resting potentail?

The inside of a nerve cell is negatively charged at its resting potential, typically around -70 millivolts. This resting membrane potential is maintained by the differential distribution of ions across the cell membrane, with more sodium and calcium ions outside the cell and more potassium ions inside.


Is a cells resting state -50 to about 50 millivolts?

No, a cell's resting membrane potential is typically around -70 millivolts. This negative charge inside the cell is maintained by the sodium-potassium pump, which pumps sodium out and potassium in, creating a voltage difference across the cell membrane.


What does the difference in the K and Na concentration on either side of the plasma membrane and permeability of the membrane to those ions generate?

The difference in concentration of K+ and Na+ across the plasma membrane, along with the membrane's permeability to these ions, generates the resting membrane potential. This potential is essential for maintaining electrical excitability in cells, such as neurons and muscle cells, and is involved in processes like nerve signaling and muscle contraction.


How does potassium affect the resting membrane potential of the cardiac cell?

Potassium plays a crucial role in maintaining the resting membrane potential of cardiac cells. It helps establish the negative charge inside the cell by moving out of the cell through potassium channels. This outward movement of potassium ions contributes to the polarization of the cell membrane, creating a negative resting membrane potential.


Which cells cause resting membrane potentials to continually depolarize?

Cells with unstable resting membrane potentials, such as pacemaker cells in the heart or neurons in the brain, can continually depolarize due to the presence of a "funny" current (If) that slowly depolarizes the cell until it reaches the threshold for an action potential to be generated.


Why is the resting membrane potential negative in cells?

The resting membrane potential in cells is negative because of the unequal distribution of ions across the cell membrane, particularly the higher concentration of negatively charged ions inside the cell compared to outside. This creates an electrical gradient that results in a negative charge inside the cell at rest.