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Agranulocytosis means a failure of the bone marrow to make enough white blood cells (neutrophils). Bone marrow is the soft tissue inside bones that helps form blood cells.
Alternative NamesGranulocytopenia; Granulopenia; Neutropenia
Causes, incidence, and risk factorsAgranulocytosis is one cause of a person not having enough of a specific type of white blood cells, called neutrophils or granulocytes.
A low neutrophil count (neutropenia) may also occur when white blood cells are destroyed faster than they can be produced.
SymptomsPersons with this condition are more likely to develop infections.
Signs and testsSee: Blood differential test
What else can I help you with?
What antipsychotic drug may be associated with agranulocytosis?
Agranulocytosis has been associated with clozapine. This is a potentially fatal reaction, but can be prevented with careful monitoring of the white blood count.
What is agranulocytosis?
An acute condition marked by severe depression of the bone marrow, which produces white blood cells, and by prostration, chills, swollen neck, and sore throat sometimes with local ulceration.
What is the meaning of lymphocytes granulocytopenia?
Granulocytopenia-- A condition characterized by a deficiency of white blood cells.
What it is agranulocytosis?
Agranulocytosis is a serious condition characterized by a significant decrease in white blood cells called granulocytes. This condition weakens the immune system, making individuals more susceptible to infections. Common symptoms include fever, sore throat, and mouth ulcers. Treatment often involves stopping the offending medication and managing any associated infections.
What has the author Suzanne Leah Iverson written?
Suzanne Leah Iverson has written: 'In vitro and in vivo investigations into idiosyncratic drug reactions: the role of reactive metabolites produced by the target tissue in terbinafine-induced cholestatic hepatitis and antipsychotic-induced agranulocytosis'
What precautions should be taken with atypical antipsychotic drugs?
Although the atypical antipsychotics are generally safe, clozapine has been associated with severe agranulocytosis, a shortage of white blood cells.
What is the contraindications of carbimazole?
Carbimazole is contraindicated in patients with a known hypersensitivity to the drug or its components. It should also be avoided in individuals with severe liver dysfunction, as it can exacerbate liver issues. Additionally, it is not recommended during pregnancy and breastfeeding due to potential risks to the fetus or infant. Regular monitoring of blood counts is essential, as carbimazole can cause agranulocytosis in some patients.
What is Antalgin 550mg?
Antalgin 550mg is a medication commonly used for the relief of pain and inflammation. It typically contains the active ingredient metamizole (also known as dipyrone), which is an analgesic and antipyretic agent. Antalgin is often prescribed for conditions such as headaches, muscle pain, and postoperative discomfort. However, its use may be restricted in some countries due to potential side effects, including the risk of agranulocytosis.
Is dipirona sodica a narcotic?
Dipyrone, also known as metamizole or dipirona sódica, is not classified as a narcotic. It is a non-opioid analgesic and antipyretic medication used to treat pain and fever. Unlike narcotics, which are derived from opium and act on opioid receptors, dipyrone works through different mechanisms, primarily affecting the central nervous system and reducing inflammation. However, its use is restricted or banned in some countries due to potential side effects, such as agranulocytosis.
Is the painkiller baralgin banned in any countries?
Yes, Baralgin, which contains the active ingredient metamizole (also known as dipyrone), is banned or restricted in several countries due to concerns about its potential to cause severe side effects, including agranulocytosis, a serious decrease in white blood cells. Countries like the United States, Canada, and some European nations have prohibited its use. However, it remains available in several other countries where it is used as an analgesic and antipyretic.
What does it mean when absolute granulocytes is 0.0?
An absolute granulocyte count of 0.0 indicates a severe deficiency of granulocytes, a type of white blood cell crucial for the immune response. This condition, known as agranulocytosis, can result from various factors, including bone marrow disorders, certain medications, or autoimmune diseases. Patients with this condition are at a significantly increased risk of infections due to their weakened immune system. Immediate medical evaluation is essential to determine the underlying cause and initiate appropriate treatment.
What side effects does baralgin?
Baralgin, which contains the active ingredient metamizole (or dipyrone), can cause side effects such as allergic reactions, skin rashes, and gastrointestinal disturbances. A more serious risk is agranulocytosis, a potentially life-threatening condition characterized by a dangerously low white blood cell count. Other possible side effects include dizziness, headache, or changes in blood pressure. It's important to use this medication under medical supervision due to these risks.
