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AST and ALT lab

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Cards in this guide (8)
Acute liver damage (due, for example, to infection, toxins or drugs, etc.)

ALT and AST Usually greatly increased; ALT is usually higher than AST

Chronic forms of various liver disorders

ALT and AST Moderately increased

Alcoholic Hepatitis

AST is usually at least twice the level of ALT

Cirrhosis

AST is usually higher than ALT but levels are usually lower than in alcoholic disease

Bile duct obstruction, cholestasis

ALT and AST Normal to moderately increased

Cancer that has spread to the liver (metastasized)

ALT and AST Normal or slightly increased

Cancer originating in the liver (hepatocellular carcinoma, HCC)

AST higher than ALT but levels lower than that seen in alcoholic disease

Autoimmune

ALT and AST Moderately increased

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