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Do carriers have to have cystic fibrosis?
Carriers of cystic fibrosis do not have the disease themselves, as they possess one normal copy and one mutated copy of the CFTR gene. However, they can pass the mutated gene to their children. For a child to develop cystic fibrosis, they must inherit two copies of the mutated gene, one from each parent. Therefore, while carriers do not have cystic fibrosis, they play a crucial role in its inheritance.
Why does a person with Cystic Fibrosis have the genotype cc?
Cystic Fibrosis is inherited as a recessive trait. This means that both parents have to carry the allele for the defect. Both parents are Cc which means that 25% of their children will be CC (homozyous dominant and will not be able to pass the recessive allele in subsequent generations, 50% will be Cc(carriers) and 25% will be cc (homozygous reccessive and have Cystic Fibrosis).
To be a cystic fibrosis carrier do your parents have to have a cystics fibrosis gene?
Yes, since the disease is a recessive inherted trait BOTH parents must carry the gene but will not have the disease itself. Approximately 30,000 people in the United States have cystic fibrosis. An additional ten million more-or about one in every 31 Americans-are carriers of the defective CF gene, but do not have the disease. The disease is most common in Caucasians, but it can affect all races.
How can one child be born healthly and second one have cystic fibrosis?
To have a child with cystic fibrosis both parents must be a carrier or a sufferer. A carrier is a person who has one healthy gene, and one diseased gene, so they dont have cystic fibrosis but they can pass it on to their children. Children inherit one gene from each parent. To get cystic fibrosis a child must get two copies of the 'disease' gene - one from each parent. If two carriers have children, each child has a 25% chance not getting a Cystic fibrosis disease gene, 50% of being a carrier and 25% of being a sufferer. This is not affected by if the child is male or female. So essentially the answer is bad luck.
Is cystic fibrosis a rare disease?
Yes, it is a genetic, inherited disease where a child must receive 2 alleles for cystic fibrosis in order to exhibit symptoms. If a child only receives one of the recessive alleles, they are known as a carrier because they have the ability to pass that gene on to their children.
What is an fact about the cystic fibrosis?
Cystic Fibrosis Is The UK's Most Common Life-Threatening Disease. It Affects About 7500 People In The UK. It Is An Inherited Disease. People With CF Are Recommended To Have A High Calorie And High Fat Diet. Both Parents Must Pass On The Defective Gene For Any Of Their Children To Get CF. CF Can Cause Coughing Or Whezzing , Weight Loss And More Symptoms. Most Cystic Fibrosis Patients Only Live To Be Slightly More Than Thirty Years Old.
What is cystic fibrosis gene disorder?
The genes on each chromosome control specific functions of the human body. The gene on chromosome 7 produces a protein called cystic fibrosis transmembrane regulator. Mutation in the DNA level of chromosome 7 leads to the absence of this protein which leads to cystic fibrosis. Cystic fibrosis is a recessive disease. It means that both copies of the gene must be defective. An affected person will have abnormal cystic fibrosis transmembrane regulator gene on each chromosome 7. Therefore both biological parents must have an abnormal gene. One abnormal copy is inherited from each parent. A person with one normal gene and one abnormal gene is called a cystic fibrosis carrier. Cystic fibrosis carriers do not show any symptoms but they may pass the abnormal gene to their children. Therefore the parents can be either cystic fibrosis carriers or affected themselves.
Which of these is an autosomal recessive disorder?
Cystic fibrosis is an example of an autosomal recessive disorder. It is caused by mutations in the CFTR gene located on chromosome 7. Both parents must pass on a copy of the mutated gene for a child to be affected by cystic fibrosis.
How does cystic fibrosis affect oxygen getting into blood?
Cystic fibrosis is a genetic condition that leads to the production of thick and sticky mucus in the lungs. This mucus can obstruct the airways, making it difficult for oxygen to pass through and enter the bloodstream. Over time, this can lead to decreased oxygen levels in the blood and difficulty breathing.
What does heterozygous have to do with cystic fibrosis?
people who are heterozygous for cystic fibrosis are not directly affected by the disease (although there is some evidence they have more chance of getting Asama) however they do still carry the gene for CF (they are carriers) this means if they have kids with another carrier they have a 25% chance of having a CF positive child (out of four one non effected, two carriers, and one diseased)
What kind of molecule produces the symptoms of cystic fibrosis?
CF is caused by a defective chloride ion channel. There's a mutation in gene that codes for the protein which forms the channel. Chloride ions pass through it.
What are the chances of passing on the CF gene?
If the spouse he or she has the gene needed to pass on cystic fibrosis, then yes it will have children with cystic fibrosis. If the spouse does not have that gene then the child will not have cystic fbrosis but will be a gene carrier of cystic fibrosis.
