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Yi Yi Ren (Coix), sometimes called "pearl barley", is different from the barley grain that contains the gluten-like proteins problematic for those with celiac sprue. Yi Yi Ren is not believed to be allergenic.

Many people mistakenly believe that these grains are a form of barley, probably because many markets label them as "Asian barley" or "Asian pearl barley." In fact, barley is in an entirely different botanical genus, although the two plants are in the same family. Like barley, Job's tears are dense, rich in minerals, and easy to use in a variety of recipes, so the case of mistaken identity can be forgiven. The plants are also cultivated as ornamentals, incidentally, and Western gardeners may not be aware that the large grains on these grasses are perfectly edible.

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