A threshold in a neuron represents the critical level of depolarization needed to trigger an action potential. When the membrane potential reaches this threshold, voltage-gated sodium channels open, allowing an influx of sodium ions that leads to rapid depolarization. If the membrane potential does not reach this threshold, the neuron will not fire, thus preventing excessive or spontaneous action potentials. This mechanism ensures that action potentials are generated only in response to sufficient stimuli, maintaining proper signaling in the nervous system.
The axon hillock is the part of the neuron that is capable of generating an action potential. It integrates incoming signals from the dendrites and, if the threshold is reached, triggers the action potential to be propagated down the axon.
The axon hillock is the anatomical region of a multipolar neuron that has the lowest threshold for generating an action potential. This is because it contains a high density of voltage-gated sodium channels, making it more excitable compared to the soma or dendrites.
No, subthreshold stimulation is not sufficient to trigger an action potential. The membrane potential needs to reach a certain threshold level for an action potential to be generated. Subthreshold stimulation only produces graded potentials that do not reach the threshold for firing an action potential.
A neuron fires when its membrane reaches a certain threshold potential. This threshold potential is typically around -55 to -65 millivolts. When the membrane potential reaches this level, an action potential is triggered and the neuron fires.
Sub threshold depolarisation of nerves, would be the influx of sodium (and maybe efflux of potassium depending) that doesn't cause enough depolarisation for an action potential to be fired. The summation of sub threshold depolarisations may cause an AP to be released. if they 'tip the balance' far enough. Hope this helps Edit: Above answer is vague. Sub threshold depolarizations do not occur as a result of efflux of potassium, which hyperpolarizes a neuron. They can be generated as EPSPs at the post synaptic membrane or result from persistant sodium channels, which do not completely inactivate (contributing to pacemaking activity). In both cases, gradual depolarization can lead to action potential generation.
Any stimulus below the neuron's threshold potential will not result in a response, as it is not strong enough to generate an action potential. Neurons require a minimum level of stimulus intensity to reach the threshold potential and fire an action potential.
Increasing the stimulus intensity past the threshold level for a neuron will not further increase the action potential generated. Once the threshold is reached, the neuron will fire an action potential at its maximum intensity.
When a neuron reaches its threshold, it initiates an action potential. This is a brief electrical impulse that allows for communication between neurons. The action potential travels down the axon of the neuron to transmit signals to other neurons or cells.
Local potentials typically occur in the dendrites and cell body of a neuron. They involve small changes in membrane potential that do not reach the threshold for generating an action potential. These local changes in potential allow for signal integration and processing in the neuron.
During the relative refractory period, the threshold for excitation is increased compared to the resting threshold. This is because the membrane potential is closer to its resting state, making it more difficult to depolarize the cell and generate an action potential. It requires a stronger stimulus to overcome this increased threshold and trigger another action potential.
The action potential will not generate if the sodium channels are kept closed.This is because the sodium channels are responsible for the dramatic rising phase of membrane depolarization that occurs when the threshold of activation is reached. As a membrane potential gradually depolarizes (which can occur for a variety of reasons such as neurotransmitter stimulation, mechanical deformation of the membrane, etc), that membrane potential gradually comes closer to that threshold of activation. Once that threshold is reached, the voltage gated sodium channels open and allow for a dramatic influx of sodium ions into the cell. This results in a rapid depolarization which is seen as the rising phase of that upward spike noted in an action potential. Without the ability to open these sodium channels we may reach the threshold of activation, but the actual action potential will not occur.
No, hyperpolarization graded potentials do not lead to action potentials. Hyperpolarization makes the membrane potential more negative, which inhibits the generation of an action potential by increasing the distance from the threshold potential needed to trigger an action potential.