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Does sickle cell disease affect life expectancy?
yes
What is the half life red blood cell in sickle cell disease?
It can be as low as 4 days.
Top 10 questions asked about sickle cell?
What is sickle cell disease?Sickle cell disease is an inherited disorder that affects red blood cells. People with sickle cell disease have red blood cells that become hard and pointed instead of soft and round. Sickle cells cause anemia, pain and many other problems.Top2) What is sickle cell trait?If you have sickle cell trait, you have inherited the gene for sickle cell disease. Sickle cell trait does not turn into sickle cell disease. If someone has sickle cell trait and his partner has sickle cell trait they may produce a child with sickle cell disease. There are about 2.5 million people in America with sickle cell trait.Top3) If sickle cell trait is not an illness, why are people tested?Babies are tested to see if they have sickle cell disease. Teens and adults are tested mainly to see if they can have a baby with the disease.Top4) What medical problems are caused by sickle cell disease?Lung tissue damage, pain episodes and stroke. The blockage of blood flow caused by sickled cells also causes damage to most organs including the spleen, kidneys and liver.Top5) How many people have sickle cell disease?Sickle cell disease is a global health problem. In the United States it is estimated that over 70,000 people have sickle cell disease. About 1,000 babies are born with the disease each year in America.Top6) How long does a person with sickle cell disease live?The average life expectancy in America has improved. It is now in the mid 40 years of age range.Top7) Are people of African descent the only group affected?No. It is also present in Portuguese, Spanish, French Corsicans, Sardinians, Sicilians, mainland Italians, Greeks, Turks and Cypriots. Sickle cell disease also appears in Middle Eastern countries and Asia.Top8) Is there a cure?There is no universal cure for sickle cell disease. Research in gene therapy, the ultimate universal cure, is currently underway.Top9) What are some promising treatment developments?The use of hydroxyurea has shown promising results on some adult sickle cell patients. It reduces the frequency of severe pain, acute chest syndrome and the need for blood transfusions.Top10) Can people with sickle cell disease live a productive life?Yes. But like all patients with chronic disease, sickle cell patients are best managed in a comprehensive multi-disciplinary program of care and a strong extended support system.
what if the father has sickle trait, does that mean the baby will have it?
If one parent has sickle cell trait and the other parent has the normal type of hemoglobin, there is a 50% (1 in 2) chance with EACH pregnancy that the baby will be born with sickle cell trait.
Is sickle cell deadly?
Sickle cell disease can be a serious and life-threatening condition if not managed properly. Complications such as infections, acute chest syndrome, and stroke can lead to serious health issues and even death. With proper medical care, including regular monitoring and treatment, individuals with sickle cell disease can lead full and productive lives.
People who are heterozygous for sickle cell disease are generally healthy because of what?
People who are heterozygous for sickle cell disease possess one normal hemoglobin gene and one sickle hemoglobin gene, which allows them to produce enough normal red blood cells to prevent symptoms of the disease. This condition, known as sickle cell trait, provides some protection against malaria, as the presence of sickle hemoglobin can interfere with the parasite's life cycle within red blood cells.
Is sickle cell anema a sex-linked gene?
yes - no its not because a sickle cell is basically a diseased cell that is shapped like a sickle.. a disease in bloodcell - it cannot get as much oxygen as healthy blood cells
Why is sickle cell important?
Sickle cell disease is important because it is a genetic disorder that affects the shape of red blood cells, leading to pain, anemia, and organ damage. It predominantly affects people of African, Mediterranean, Middle Eastern, or Indian descent. Early diagnosis and proper management are crucial to prevent complications and improve quality of life for individuals with sickle cell disease.
Can an adult be diagnosed with sickle cell anemia?
Yes, an adult can be diagnosed with sickle cell anemia. The condition is usually detected in childhood through newborn screening or during genetic testing later in life. Adults who have not been previously diagnosed may present with symptoms such as anemia, pain crises, or complications related to sickle cell disease.
How long are you expected to live with a sickle cell trait?
Sickle cell trait should have no problems and should have a normal life expectancy
What chromosome number is affected in sickle cell disease?
Sickle cell disease is caused by a mutation on chromosome 11, specifically in the HBB gene that codes for the beta-globin protein. This mutation leads to the production of abnormal hemoglobin, resulting in the characteristic sickle-shaped red blood cells.
Can you die from sickle cell anemia?
Yes, and no. No, because when you do have sickle cell anemia, your irregular blood shape interferes with the blood's ability to carry oxygen and pass through narrow openings such as the capillary. People who have sickle cell die relatively early because of the organ damage and lack of oxygen caused by the blood's irregularity. Yes, because it has been found that people with sickle cell anemia are protected against malaria.
