It can be as low as 4 days.
some one with sickle cell anemia can not drink u know sickle cell is like half cell not complete cell and drink causes swollen of the liver so it"s dangerous and can cause sudden death.
The sickle cell trait is that you dont have the whole thing you have half of it which is called the trait
It is a genetic disorder. However... It is also a protection against malaria. For example, if a person were born in an area where malaria is present, he or she would likely die from the disease, unless he or she inherited 1 sickle cell gene. Malaria viruses reproduce in the red blood cells. The parent virus invades a cell, and uses the cell as a host to grow more viruses. With 1 sickle cell gene, malaria viruses that invade a red cell are quickly destroyed, since the red cell collapses, preventing the virus from reproducing. But with 2 sickle cell genes, red cells collapse too easily; just a bruise can cause someone to become anemic when too many red cells collapse. In the real world, people with no sickle cell genes died from malaria. People with 1 sickle cell gene survived. People with 2 sickle cell genes died from sickle cell anemia. It was natures way of assuring that at least half of the population survive, but it is certainly a difficult thing to live with today, now that we can more easily treat malaria.
Sickle cell has a different shape due to a genetic mutation, causing the red blood cells to be rigid and form a sickle shape. This can block blood flow and decrease the cell's ability to carry oxygen efficiently. Normal red blood cells are flexible and can move freely through blood vessels to deliver oxygen.
Normally, the 6th position of the beta chain of hemoglobin is a Glutamic acid, encoded on the DNA as GAG. The sickle cell mutation has the sequence GTG, resulting in a Valine in the 6th position instead.
Sickle-cell Anemia, or Sickle-cell Disease, is a disease which is caused by a mutation in the animo acid sequence of the red blood cells.The type of mutation occurs during the transcription of messenger RNA (e.g. GTC becomes CCG instead of CAG ). This change causes the mRNA to translate into a different amino acid (e.g. Valine instead of Glutamate ).In this disease, the changes start in amino acids, the primary structure of proteins, thus changing all the higher protein structures. The red blood cells then will have a different shape, like a sickle.These sickle shaped red blood cells will nor function normally. Thier shape disables them from flowing easily in the blood vessels, which might lead to further complications. Also, their life span is shorter than the normal cells, hence causing Anemia.See the Related Link.A chronic, inherited blood disorder characterized by crescent-shaped red blood cells. It occurs primarily in people of African descent, and produces symptoms including episodic pain in the joints, fever, leg ulcers, and jaundice.
Sickle cell anemia is a genetic diseases that causes red blood cells to be shaped like sickles while normal red blood cells are shaped more like a cylinder. Malaria works by going into the red blood cells until they burst. Because of the strange shape of the red blood cells in people who have sickle cell anemia, malaria can't enter in the cells that have the sickle trait, but it can enter in the others. This way, people with sickle cell wouldn't be as adversely effected then those without it.
Basically, sickle cell anemia means that some of the red blood cells of the person with the disease are not the right shape, instead of being bowl shaped, they are half moon shaped. This means that they can't carry oxygen around the body as well as a person without the condition. As the sickle cells are not only the wrong shape, but also quite rigid, they can block the blood capillaries, so that tissues in the body become starved of oxygen (ischemic). The blockages can vary loads in severity/frequency etc, and they can end up causing a stroke or heart attack if blocking a blood vessel to the brain or heart. One of the organs that is really badly affected by this is the spleen. It has really narrow blood vessels leading to it, so can get starved of oxygen badly and frequently. Normally this means that people with sickle cell anemia do not have a working spleen by the end of childhood, so are at risk of infections. People with sickle cell anemia tend to have more red blood cells than people without the condition as their body over compensates for the red blood cells.
If both parents are trait carriers the chances of them having a child WITH sickle cell is 4 to 1. Probability says, 1 will not carry the trait OR have sickle cell, 2 will be trait carriers and 1 will have it. But Keep in mind that every time you have a child its like rolling dice. I have heard of people where all four kids have the disease. and i have 2 children with the disease and 1 that's normal.
When cells don't form a membrane and are only half developed and then pass thus genetic information onto other cells...i think Sickle cell anemia is a condition in which the red blood cells are misformed. Instead of being round and concave somewhat like a donut but without a hole, a sickled red blood cell looks more like a crescent moon. The problem with sickle cell anemia is that, because of the deformity, it is not able to carry as much heme therefore decreasing the amount of oxygen each red blood cell can carry. When individuals get into sickle cell crisis, the cells of their body are greatly deprived of oxygenated blood. They are usually dehydrated and thus the sickled cell has even more difficulty passing through the venous and arterial systems. This condition is extremely painful for the individual and they will need medical attention immediately.
Basically, sickle cell anemia means that some of the red blood cells of the person with the disease are not the right shape, instead of being bowl shaped, they are half moon shaped. This means that they can't carry oxygen around the body as well as a person without the condition. As the sickle cells are not only the wrong shape, but also quite rigid, they can block the blood capillaries, so that tissues in the body become starved of oxygen (ischemic). The blockages can vary loads in severity/frequency etc, and they can end up causing a stroke or heart attack if blocking a blood vessel to the brain or heart. One of the organs that is really badly affected by this is the spleen. It has really narrow blood vessels leading to it, so can get starved of oxygen badly and frequently. Normally this means that people with sickle cell anemia do not have a working spleen by the end of childhood, so are at risk of infections. People with sickle cell anemia tend to have more red blood cells than people without the condition as their body over compensates for the red blood cells.
It could be possible, but quite unlikely. The gene is of African origin. Here is how the odds work: 1. If only one parent has the trait, there is a 50% chance that a child of theirs would also just have the trait without having the full-blown disease. 2. If two parents has the trait, then any children would be 25% like to not have the trait at all, 50% likely to be a carrier, and 25% likely to have the full-blown disease. 3. If a person has the disease and the other parent doesn't have the trait at all, then all resulting children would carry the trait but not have the disease. 4. If a person with sickle cell anemia has children with a carrier, then half the children would have the disease, and half would have just the trait. 5. Assuming 2 people with sickle cell anemia are alive long enough to have children together, all their children would have it. So back to the question. If one parent was White and the other was Black with the sickle cell trait and not the full-blown disease, then they would not have children with the disease, but roughly half would carry it. But if the Black parent was born with the disease (both genes), then none of the children would have it, but all would be carriers. But typically, neither parent would even have the trait, and so none of the children would get it or carry it. Now, lets suppose that two interracial persons produce children together. If by chance they both carried the trait, then the odds are 1 in 4 of having the disease, 1 in 4 of not even carrying it, and a 50% chance of being a carrier.