yes
- no its not because a sickle cell is basically a diseased cell
that is shapped like a sickle.. a disease in bloodcell
- it cannot get as much oxygen as healthy blood cells
Sickle cell Anemia is auto somal. because it's chromosomes don't separate
No
This is inherited on the X chromoseome and is recessive. This means a female (who has XX chromosome pair) can only express the disease if she carries the trait on both chromosomes. This is because of the recessive nature of the gene. A male can only inherit the disease from his mother. This is he must have obtained his Y chromosome from his father so he obtains the X chromosome from his mother. A male cannot carry the gene without expressing it as he doesnt have another X chromosome to supress the recessive gene. ^ This answer is biologically incorrect because Sickle cell Anemia is actually autosomal recessive, not sex-linked recessive; this means that males and females are affected equally and it is NOT carried on the X chromosome. In order for the trait to show up in an individual, BOTH parents must be carriers of the disease (at least 1 sickle cell gene must be present).
Under blood group, the letters AS and SS are used in reference to sickle cell disease. AC means that one is carrying the sickle cell disease gene while SS means that one has sickle cell disease.
change in DNA that caused sickle cell disease
*An allele is basically the different forms a particular gene can take (describes the various genotypes/phenotypes a gene can take).* For example there is an allele of a gene which codes for haemoglobin in red blood cells, which gives them their characteristic concave shape. But there can also be a mutation in that gene, which causes a different allele to be produced which gives it a sickle-cell shape, which leads to sickle-cell anaemia.
If both parents are trait carriers the chances of them having a child WITH sickle cell is 4 to 1. Probability says, 1 will not carry the trait OR have sickle cell, 2 will be trait carriers and 1 will have it. But Keep in mind that every time you have a child its like rolling dice. I have heard of people where all four kids have the disease. and i have 2 children with the disease and 1 that's normal.
Sickle Cell Anaemia is a single gene defect (Hb gene).
A child has to receive the gene from both parents to heve sickle cell anemia. if only one parent passes on the gene, then the child will have sickle cell trait, but no symptoms of sickle cell anemia.
If one represents a sickle cell gene thus "C" and a normal gene thus "O" then both parents are: Mum CO Dad CO The possibilities for their children are therefore CC OO CO CO in those proportion so 1in 4 will have sickle cell anaemia, 2 in 4 will be carriers (like their parents) and 1/4 will be normal.
No, it's not a one gene disorder
The person is homozygous for the trait
If you carry the sickle cell gene, it doesn't really mean much as far as your own personal health goes. Except that you are less likely to get malaria. However, if you decide to have kids, and whoever you mate with also carries the sickle cell gene (not the full blown disease/gene) , your child has a chance of having sickle cell disease (full blown).
you dont have to worry about getting sickle cell if your not african american
malaria
autosomal recessive
yes
A person with one sickle cell is a "carrier". This means that they have the dormant cell in their genetic composition, and if combined with another with the "carrier" gene, they run the high risk on concieving a child with the blood disease-one who has two sickle cells. A person with two sickle cells, has the sickle cell disease and are carriers(The gene is not dormant but active). Hope this simplifies and explains it for you.
While technically there are more than one, the main one by far is sickle cell anemia.