Yes, Klinefelter's syndrome is due to the XXY genotype.
xxy
non disjunction of sex chromosomes
non disjunction of sex chromosomes
46,XXY or XXY for males; see the link below.
Causes of Klinefelter SyndromeThe additional sex chromosomes in men with Klinefelter syndrome results from nondisjunction during meiosis and may have a paternal (50 to 60 percent) or maternal (40 to 50 percent) origin. This contrasts with Down syndrome, which is caused predominantly by maternal nondisjunction and inheritance of the extra chromosome 21 from the mother.
By definition Klinefelter's syndrome is genetically XXY. If there is any Y chromosome present, the baby will develop into a boy. Even if a baby had XXXXY, it would still turn out as a boy.
Klinefelterâ??s syndrome is the result of additional X genetic material in males and typically causes low testosterone levels, gynecomastia, and infertility. Though there are no documented famous people with this syndrome, some believe that George Washington may have been afflicted.
It could be a problem very early in development (during pregnancy). About 1/3 of all males with Klinefelter syndrome have other chromosome changes involving an extra X chromosome.This syndrome isn't considered an inherited condition.Klinefelter's syndrome is not hereditary. And males who have this disease are infertiled. It means that they can't produce offspring because they can make few sperms.
No " following, but a condition such as trisomy 21, Downs syndrome, is caused by nondisjuction. The chromosomes fail to separate properly and one child is left with an extra chromosome number 21. The potetial other children that could have been born of this nondijuction event, those with only one chromosome 21, are not viable.
Non-disjunction can result in a number of different conditions, including Down Syndrome, Klinefelter Syndrome, Turner's Syndrome, Super Males, Triple X syndrome or Edward's Syndrome.
Klinefelter syndrome is a chromosomal condition that only affects males and is characterized by a male having an additional X chromosome (XXY) in cells. This chromosome abnormality occurs when there is an error in cell division, resulting in an extra copy of the X chromosome.
No, as people with Klinefelter's syndrome cannot have children and so there would not be another generation. (That is not entirely true, while it is true Klinefelters causes an extra chromosome sperm maybe be found via a testicular extraction in minute amounts. If this is the case you can father a biological child though the chances are small it is not impossible and more and more Klinefelter men are becoming dads. We can also adopt, and while I understand the authors point - the child would be ours and therefore carry our name and continue the generation. Klinefelters IS NOT hereditary. Hope this helped.
The parents have normal sex chromosome genotypes, XX and XY. The chromosomal error that causes Klinefelter's syndrome occurs during the formation of either of the parent's gametes during meiosis.