The glucose transporter that is activated by insulin (glut 4) is a prime example.
The glucose transporter that is activated by insulin (glut 4) is a prime example.
The glucose transporter that is activated by insulin (glut 4) is a prime example.
Insulin plays a crucial role in regulating glucose homeostasis by promoting the translocation of the glucose transporter type 4 (GLUT4) to the cell membrane, particularly in muscle and adipose tissue. When insulin binds to its receptor on these cells, it triggers a signaling cascade that facilitates the movement of GLUT4-containing vesicles to the surface, allowing glucose to enter the cells. This process is essential for lowering blood glucose levels and is impaired in insulin resistance and type 2 diabetes. Thus, insulin and GLUT4 work together to manage glucose uptake effectively.
Insulin is what catabolises (breaks down) glucose following a high carbohydrate meal. Diabetes has 4 types: only type 1 diabetes is related to insulin (seen in children and adolescents). It is called Insulin-Dependent Diabetes. Diabetes is basically very high levels of glucose found in the blood (greater then 250mg/dl) after testing. Where, normal fasting ranges of glucose = 70-110mg/dl Type 1: If their is a severe lack of insulin in the body. Glucose is unable to be broken down by the body (by stomach juices), because glucose is "dependent" upon insulin to be broken down causing diabetes (high levels of glucose in the body).
The glucose transporter that is activated by insulin (glut 4) is a prime example.
There are a number of causes for low glucose.. 1) Low dietary intake 2) Diabetes mellitus as in no insulin release 3) Taking an insulin injection/parenteral insulin 4) Bacteria can cause it as they will eat it all up if u have bacterimea
I know three out of six steps. 1. ? 2. Blood glucose levels increase. 3. ? 4. Glucose is stored in the liver. 5. ? 6. The pancreas releases glucagon. By Group 935[Chris]
Insulin response comes about from receptor tyrosine kinase. When insulin binds to the alpha portion of the RTK, the receptors dimerize. This results to its beta intracellular portion to autophosphorylate. This creates a binding site for IRS-1. When IRS-1 is activated, it recruits glut-4 receptors, allowing glucose to be taken in from the blood (therefore blood conc. will fall under insulin)
Insulin is released by the pancreas, and serves two important functions in blood-glucose control. Firstly, it encourages muscle and liver cells to take glucose from the blood. This is all very well, but glucose is soluble in the cytoplasm, and this poses a problem for osmoregulation, in the cells, so insulin also stimulates the conversion of glucose into glycogen - an insoluble sugar, which can then be stored until it is needed for respiration by cells.
The type of insulin that typically peaks within 2-4 hours is known as short-acting insulin. Examples of this category include regular insulin, which is often used to manage blood glucose levels during meals. This insulin works quickly to lower blood sugar but has a shorter duration compared to longer-acting insulins. It is important for individuals using short-acting insulin to monitor their blood sugar levels to avoid hypoglycemia during its peak action time.
Glucose transport into muscle cells is primarily facilitated by the glucose transporter 4 (GLUT4) carrier protein. This transporter is insulin-responsive and plays a crucial role in regulating glucose uptake by muscle cells to meet energy demands during exercise and recovery.