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Activity intolerance can be caused by a variety of factors, including physical deconditioning, chronic illnesses (such as Heart disease, respiratory disorders, or Diabetes), and psychological issues like anxiety or depression. Additionally, pain, fatigue, or side effects from medications can limit an individual's ability to engage in physical activity. Environmental factors, such as a lack of access to safe exercise spaces, can also contribute to decreased activity levels. Overall, a comprehensive assessment is often needed to identify the underlying causes for effective management.

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