Melanocytes are cells that arise from the neural crest during development and migrate to the epidermis. They are responsible for producing the pigment melanin, which contributes to skin color and protection from UV radiation.
langerhans cells. They orriginate in bone marrow and migrate to the epidermis.
Yes. Epidermal dendritic cells arise from bone marrow and migrate to the epidermis. They are also called Langerhans cells after a German anatomist. These cells ingest foreign substances (phagocytic) and are key activators of our immune system.
The major skin area from which the derivatives arise is the stratum basale, which is the deepest layer of the epidermis. This layer contains stem cells that continuously divide and differentiate to give rise to the various cell types in the epidermis, including keratinocytes, melanocytes, and Merkel cells. These cells migrate upwards through the layers of the epidermis to replenish and repair the skin.
T cells and B cells both arise from hematopoietic stem cells in the bone marrow. They undergo differentiation and maturation in the thymus for T cells and in the bone marrow for B cells.
Immature lymphocytes arise from hematopoietic stem cells in the bone marrow. They undergo maturation and selection processes in the bone marrow (B cells) and thymus (T cells).
Bloods cells arise from the bone marrow.
Langerhans cells are a subset of dendritic cells that reside in the epidermis (Part of the immune system). They have long dendrites (like arms) that capture antigen in the skin, and when they find an antigen they migrate to lymph nodes and present to T cells allowing the adaptive immune system to respond.
The reproducing cells of the epidermis are found in the stratum basale or basal layer, which is the deepest layer of the epidermis. These cells continuously divide and give rise to new skin cells that eventually migrate to the surface of the skin.
B cells and T cells migrate to secondary lymphoid organs such as lymph nodes and spleen to carry out their immune functions. Here, they encounter antigens, undergo activation, and differentiate into effector cells to mount an immune response.
There are two types of bone marrow: red marrow (consisting mainly of myeloid tissue) and yellow marrow (consisting mainly of fat cells). Red blood cells, platelets and most white blood cells arise in red marrow. Both types of bone marrow contain numerous blood vessels and capillaries.
T-lymphocytes are produced in the bone marrow from hematopoietic stem cells. They mature in the thymus, hence their name "T cells."