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When you don't have enough insulin in your body, your body starves for energy (which normally comes from glucose, and is permitted into the cells by insulin.) In response, fat is converted by the liver into Acetoacetate and Beta-hydroxybutyric acid, known as ketone bodies. These supply energy to the body in emergencies.

Normally this condition would be temporary and normal insulin production would put a quick stop to it. But in an insulin-dependent diabetic, that insulin doesn't arrive and so the ketone bodies begin building up in the blood and urine. Ketone bodies are acidic and so they affect the blood's pH balance.

The body must maintain a pH balance of 7-7.25. 7 is neutral but anything lower causes an acidotic situation, meaning the blood turns acidic. Once that happens, things get worse.

Symptoms include stomach tenderness, lethargy, fever, vomiting, and ketone-smelling breath. (Breath may smell like nail-polish remover, pear drops, or fruit.)

An advanced symptom is Kussmaul's respirations: Characterized by short,deep, and rapid breathing. This is the mechanism the body uses in an attempt to regulate the bodys' pH balance. The body is trying to "blow out " the CO2 or carbon dioxide that has accumulated.

In addition, the body continues calling out for energy that it can't get due to missing insulin, so more glucose is dumped into the blood leading to severe hyperglycemia. More ketone bodies are still being produced too. The hyperglycemia and acidosis each cause the kidneys to flush out water, leading to severe dehydration. The dehydration leads in turn to worse acidosis and hyperglycemia (since the blood is more concentrated).

By now the blood's electrolytes (Potassium especially) are thrown out of balance and things get really bad. At this point treatment becomes tricky and survival rate is about 90% only if full emergency hospital treatment is at hand.

If you are diabetic and think you have diabetic ketoacidosis, then

1. Drink a lot of water right now.

2. Take some of your regular insulin. If you have a slow-acting and a fast-acting insulin for mealtimes, take the fast one. If you have oral diabetic medications, don't take those.

3. Get an ambulance now, and mention diabetic ketoacidosis emergency on the phone.

More details at the Wikipedia article linked below.

Dehydration and shortage of insulin and High ketone levels together over a short period of time can cause DKA. If you start vomiting and you have many of the other symptoms you are most likely going or are in DKA.

Symptoms include: Acetone or fruity smelling-breath, dehydration, stomachache, fever, possible vomiting, lethargy, high and rising blood sugar, hyperventilating (see Kussmaul breathing). If you have ketone strips for your urine, you will see a high ketone level.

If you think you are in DKA:

1. Drink as much water as you can

2. Take some of your fastest-acting insulin

3. Call an ambulance and say you think you are in DKA.
You mean "Diabetic Ketoacidosis", check for it on Google. There's no such thing as diabetic keratosis.

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15y ago

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Related Questions

What is the medical term meaning the condition causing fruity breath in a diabetic?

The fruity acetone breath is a sign of ketoacidosis.


Ketoacidosis associated with diabetes mellitus is likely to produce what acid imbalance?

Ketone production in diabetes causes a condition called diabetic ketoacidosis, which is a form of elevated anion gap metabolic acidosis.


What are kussmaul respirations?

deep, rapid breathing usually as compensation for a metabolic acidosis, especially that seen with Diabetic Ketoacidosis - as a result of too much sugar in the bloodNote that at onset, it is shallow and as metabolic acidosis develops, it becomes deep and rapid. This is commonly seen in patient facing imminent death due to multiple organ failure particularly the kidneys secondary to hyperglycemia.KUSSMAUL RESPIRATIONS IS THE DEEP, RAPID, AND LABORED BREATHING ASSOCIATED WITH ACIDOTIC STATES, PARTICULARY DIABETIC KETOACIDOSIS (DKA)k= ketonesu=uremias=sepsiss=salicylatesm=methanola=aldehydeu)l=lactic acidosis


What is diabetic keratosis?

You mean "Diabetic Ketoacidosis", check for it on Google. There's no such thing as diabetic keratosis.


What three features does diabetic ketoacidosis combine?

hyperglycemia, meaning excessively high blood sugar kevels; hyperketonemia, meaning an overproduction of ketones by the body; and acidosis, meaning that the blood has become too acidic.


Where can I find information about diabetic ketoacidosis?

Diabetic ketoacidosis is a condition which is thought to affect about 1 in 750 people in their lifetime. More information can be obtained from reputable medical journals or a doctor.


Can fat metabolism result in acidosis?

Yes. Ketoacidosis is a product of the breakdown of fatty acids.


Which condition may progress to diabetic ketoacidosis?

Diabetes, if untreated.


A patient is described as being diabetic and having Kussmaul respirations. What physiologic activity is taking place to cause this in your patient?

This sign is indicative of diabetic acidosis. The deep, rapid respirations will raise the patient's pH, thus reducing the acidotic condition. Sounds right -- I've heard it called ketoacidosis too.


What causes the a decrease in HCO3?

A decrease in bicarbonate (HCO3) levels can be caused by conditions such as metabolic acidosis, kidney dysfunction, diarrhea, or excessive loss of bodily fluids. Additionally, it may result from disorders affecting the pancreas, such as diabetic ketoacidosis or pancreatitis.


What would a Serum potassium level of 2.8 indicate?

Diabetic ketoacidosis


Is ketoacidosis diabetic retinopathy and nephropathy may be complications of iddm?

FALSE