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Amyloid substances resemble fibrous protein aggregates that have an abnormal structure, often forming insoluble plaques. They typically have a beta-sheet configuration and can appear as elongated fibrils under an electron microscope. In tissues, they can create a waxy, translucent appearance and are commonly associated with various diseases, such as Alzheimer's and amyloidosis.
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What is an amyloid?
An amyloid is a waxy compound of protein and polysaccharides which is found deposited in tissues in amyloidosis.
What is another name for Cerebral amyloid angiopathy?
Cerebral amyloid angiopathy (CAA) is also known as congophilic angiopathy or cerebrovascular amyloidosis.
What substances does a low-order explosive resemble when exposed to air and sun light?
Dark brown rocks
What is amylodiosis?
A disorder marked by deposition of amyloid in the body. a rare disease which causes the build-up of amyloid, a protein, & starch, it can get in tissues and organs.
Signs of amyloid proteins can be indicated by?
Blood and urine test
How does amyloidosis occur?
Amyloid proteins are manufactured by malfunctioning bone marrow. Amyloidosis, which occurs when accumulated amyloid deposits impair normal body function, can cause organ failure or death.
What has the author Dankwart Stiller written?
Dankwart Stiller has written: 'Histochemistry of amyloid' -- subject(s): Amyloid, Amyloidosis, Analysis, Cytologic Diagnosis, Electron microscope, Histochemistry, Ultrastructure (Biology)
Where does solanezumab derive from?
Solanezumab is a monoclonal antibody that was developed by Eli Lilly and Company. It specifically targets amyloid-beta peptides, which are associated with the formation of amyloid plaques in the brains of Alzheimer's disease patients. The antibody was designed to bind to soluble forms of amyloid-beta, aiming to modify the disease's progression. Its development was part of ongoing research into potential therapies for Alzheimer's.
What is the difference between amyloid beta protein and tau protein?
== == Amyloid beta (AB) protein is produced from the cleavage of amyloid precursor protein (APP: a transmembrane protein) by beta secretase and gamma secretase. The build up of this intact AB protein leads to formation of amyloid plaques. Tau is a group of microtubule associated proteins which contributes to the assembly and stabilization of microtubules in axons. However, hyperphosphorylation of tau leads to tau aggregation and formation of neurofibrillary tangles (NFT). Intracellular NFT and extracellular amyloid plaques are two pathological hallmarks of Alzheimer's disease.
Was are Brain lesions associated with Alzheimer disease called?
amyloid plaques Sheaths
How is amyloidosis treated?
The goal of treatment is to slow down or stop production of amyloid protein, eliminate existing amyloid deposits, alleviate underlying disorders (that give rise to secondary amyloidosis), and relieve symptoms caused by heart or kidney damage.
What is protein type AAA?
AmyloidosisIn medicine, amyloidosis refers to a variety of conditions in which amyloid proteins are abnormally deposited in organs and/or tissues. A protein is described as being amyloid if, due to an alteration in its secondary structure, it takes on a particular aggregated insoluble form similar to the beta-pleated sheet. Symptoms vary widely depending upon the site of amyloid deposition. Amyloidosis may be inherited or acquired.(Extracted from Wikipedia.)
