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Premature ovarian failure (POF), also known as primary ovarian insufficiency, occurs when the ovaries stop functioning normally before the age of 40, leading to decreased estrogen production and disruption of the menstrual cycle. This can result in symptoms such as irregular or absent periods, infertility, and menopausal symptoms like hot flashes and mood swings. The condition may be caused by genetic factors, autoimmune disorders, or environmental influences, though in many cases the exact cause remains unknown. Women with POF may require hormone replacement therapy to manage symptoms and maintain bone health.

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1w ago

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