0
What is a simple explanation and symptoms of the diagnosis of iron overproduction and being homozygous for the C282Y mutation?
Hemochromatosis is a commonly inherited disorder where the body does not deal with iron properly. It doesn't necessarily mean that you produce too much iron, just that it is improperly stored in the body tissues, especially the liver. It is possible to be anemic and have hemochromatosis!
Being homozygous for the gene means you have probably inherited it, although your parents may or may not have had it. It would be a good idea if any of your siblings were also tested as there is a very high chance they may have inherited it as well.
If left untreated it can cause all manner of diseases as the organs are slowly damaged by the excess stored iron. Many people have this disorder but don't know they do. They may, however have various heart, liver, or pancreatic problems to name but a few. The treatment is usually by venesection, which simply means blood is taken from you which forces some of the stored iron to be released, thus reducing the level in the liver. It is well worth persevering with this treatment as it is a lifesaver.
For further information, see the Related Links below.
What else can I help you with?
What does the age at diagnosis tell you about the mutation?
The age at diagnosis can provide information about when the mutation began to have an observable impact on health. For some conditions, an earlier age at diagnosis may suggest a more severe form of the disease associated with the mutation. Conversely, a later age at diagnosis may indicate a milder or variable expression of the condition.
If a male homozygous for the normal gene order and a female homozygous for an inversion mutation had a child the child would have what type or types of chromosomes?
The child would inherit one set of chromosomes from each parent. Since the male is homozygous for the normal gene order, he will pass on a normal chromosome set. The female, being homozygous for the inversion mutation, will pass on chromosomes that carry the inversion. As a result, the child will have one set of normal chromosomes and one set with the inversion mutation, leading to a genotype that is heterozygous for the inversion.
What is an individual who has the genotype DD called?
homozygous first filial organism,which can undergo mutation or which may be cross-linked or made to breed with other.
What is the difference between genetic a disorder and a genetic mutation?
Mutation is any change in the genetic code of an individual regardless of how the change manifests. A genetic disorder is the result of an unfavorable mutation that results through through heterozygous recessive parents producing a homozygous recessive offspring, a random dominant mutation, or multiple polygenic mutations that compound for a negative effect on an individual as examples.
What is a X linked carrier homozygous?
An X linked carrier is one who carries a mutation in a gene found on the X sex chromosome. A carrier of the trait doesn't display phenotypic symptoms of the disease or mutation but can transfer the mutation in that gene to their offspring (ex: the carrier of a premutation that when transferred to the offspring via the X chromosome will cause the full mutation associated with that gene). A person could be a homozygous carrier if for instance, she were female (two X chromosomes) and carried the premutation associated with the disease. Some diseases need both alleles of the gene to be mutated. If only one allele is mutated (heterozygote) that person may be a carrier for that mutation and can thus pass on that mutation to their children.
What is the genotype of a person that is homozygous non sicklier?
The genotype of a person who is homozygous non-sickler for sickle cell anemia would be HbAHbA, meaning they have two normal hemoglobin genes. This genotype does not carry the mutation that causes sickle cell anemia.
Anther culture has benefits than embryo culture justify?
Through anther culture only we can get homozygous line. recessive charcters too get a chance to express. mutation studies are more feasible.
What is the difference between homozgous and heterozygous?
Heterozygous vs. Homozygous: These terms refer to genetic mutations. There are two copies of the protein codes in the genetic code. If one copy is normal and the other has the mutation, it is said to be heterozygous. If both copies have the mutation, it is said to be homozygous. For example: A/A -- homozygous. A/a -- heterozygous. a/A -- heterozygous. a/a -- homozygous.Homologous refers to the pair of chromosomes that are the same whilst Homozygous refers to the fact that alleles of a gene pair are the same
What does Homozygous Positive mean?
Homozygous positive refers to an individual who has two identical alleles for a specific gene, both of which carry a dominant trait or mutation. In genetics, this term is often used in the context of certain tests, such as those for genetic disorders or traits, indicating that the individual has inherited the same allele from both parents. This can have implications for traits, diseases, or characteristics associated with that gene.
What is the treatment for mthfr c677t?
I have the c677t mutation homozygous and my doctor has me on Metagenics Vessel Care, vitamin D3 and omega 3 oil. I'm not sure how well its working yet. Eat organic food and stay away from chemicals if you have this.
Which genotype will give rise to the Bombay phenotype?
The Bombay phenotype is caused by a homozygous recessive mutation in the FUT1 gene, which results in the absence of H antigen on red blood cells. Therefore, the genotype for the Bombay phenotype is hh.
If a strand of DNA with the sequence TGA mutated to GCA would it be a silent or missense mutation?
Both a silent and missense mutation is a change in one nucleotide. However, a silent mutation still codes for the same amino acid, but a missense mutation codes for a different amino acid. This means that a silent mutation will have no affect on the resulting protein, but a missense mutation will. Still, it is not guaranteed that a a missense mutation will result in a disfunction of created protein, as long as it is not occurring in the activation site.
