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It's the Brand name for the Generic drug Cyclophosphamide, a chemotherapy drug.

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11y ago

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What is the treatment for Wegener's granulomatosis?

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One molecule of Cytoxan, also known as cyclophosphamide, contains 19 atoms. This includes two nitrogen atoms, eight hydrogen atoms, two oxygen atoms, four carbon atoms, and three phosphorus atoms.


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There are 4 Food and Drug Administration medications for the treatment of lupus:AspirinPrednisoneHydroxychloroquine (Plaquenil)Belimumab (Benlysta)Off label medications include prescription anti-inflammatories, rituxan (Rituxamab), cytoxan, azathioprine, methotrexate and other immunosuppressive medications.


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What are the Five major types of alkylating agents?

žNitrogen mustards: such as mechlorethamine (nitrogen mustard), chlorambucil, Cyclophosphamide (Cytoxan), ifosfamide, and melphalanžžNitrosoureas:streptozocin, carmustine (BCNU), and lomustinežAlkyl sulfonates: busulfanžžTriazines: dacarbazine (DTIC) and temozolomide (Temodar)žžEthylenimines: thiotepa and altretamine (hexamethylmelamine)žThe platinum drugs (cisplatin, carboplatin, and oxalaplatin) are sometimes grouped with alkylating agents because they kill cells in a similar way.


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Medications vary widely based on what organs are affected by the autoimmune activity. Antimalarials, prednisone and NSAIDS are used most commonly. Chemotherapies like methotrexate and cytoxan are sometimes used. Cellcept (mycophenolate mofetil) which is used to prevent organ transplant rejection is now being used for many lupus patients. New biologics are being developed which interrupt the autoimmune activity at the level of B cells. Benlysta is on its way to FDA approval and will be the first new medication developed and approved specifically for lupus since November 20, 1958.


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Lupus is an autoimmune disease that can affect any part of the body. Lupus affects each patient differently. Because of that, a variety of medications are used to manage lupus, many of them "off label" or not approved by the FDA for treatment of lupus. The four drugs approved by the FDA are aspirin, hydroxychloroquine, prednisone and Benlysta (belimumab) which is give by IV infusion. Subcutaneous clinical trials are now underway for Benlysta. Off label drugs include methotrexate, azathioprine, cytoxan, mycophenolate mofetil, rituximab and a variety of non steroidal anti inflammator medications.


Cyclophosphamide (Cytoxan and reg) 4 mgkg per day po has been ordered. The patient weighs 154 lbs. How many milligrams should be given each day?

To calculate the daily dose of cyclophosphamide, first convert the patient's weight from pounds to kilograms. The patient weighs 154 lbs, which is approximately 70 kg (154 lbs ÷ 2.2 lbs/kg). Then, multiply the weight in kg by the dose in mg/kg: 70 kg × 4 mg/kg = 280 mg. Therefore, the patient should be given 280 mg of cyclophosphamide each day.


Is there a cure for sarcoidosis?

Corticosteroid drugs remain the primary treatment for inflammation and granuloma formation. There is no treatment at present to reverse the lung scarring (fibrosis) that might be present in advanced sarcoidosis. Because sarcoidosis can disappear even without therapy, even doctors sometimes disagree on when to start the treatment. Various other drugs have been tried, but their effectiveness has not been established in controlled studies. These drugs include chloroquine (Aralen) and D-penicillamine. Several drugs such as chlorambucil (Leukeran), azathioprine (Imuran), methotrexate (Rheumatrex, Trexall), and cyclophosphamide (Cytoxan), which might suppress alveolitis by killing the cells that produce granulomas, have also been used.