As far as number of people killed per year, Heart disease is the number one killer in the US.
The most deadly infectious disease in history was the pneumonic form of the plague, the so-called black death of 1347 to 1351. The pneumonic plague,which was a bacterial lung infection, had a mortality (death) rate of 100%.
Another answer:
Ebola is widely considered the "nastiest" of viral diseases. It is compared to AIDS in many ways. Fortunately, Ebola virus is not extremely common, but when there is an outbreak it is noted as extremely deadly. It is considered one of the most Infectious Diseases due to it being able to spread quite easily through the transaction of body fluids (a dirty needle is a major cause, and, like AIDS, it is noted for its ability to travel through sexual intercourse. This is more famous for Ebola's twin- less deadly- virus, Marburg). Ebola is also able to travel in the air, but it does so with difficulty.
There's never been a major outbreak outside of Africa, though small occurrences due pop up around the world. Marburg- the twin virus- is named for its breakout in Marburg Germany.
Ebola- not counting Marburg- has two prominent subspecies, but a few more: Ebola Sudan and Ebola Zaire.
Marburg is the least deadly, with a mortality rate below 50%.
Sudan is slightly worse, with a mortality rate just below 70%.
Zaire is considered the worse, with a mortality rate measuring above 90%.
The events recorded in the true story-novel, "The Hot Zone", are a chronicle of the story of Ebola outbreaks. It culminates in the climax of the novel outside of Washington DC where an outbreak of Ebola was barely dodged. The subspecies there was particularly deadly toward non-human primates and was discovered in the Reston monkey house in the suburb of Reston.
Ebola is perhaps not the deadliest virus due to its uncommon nature and its inability to spread as much as HIV (the virus that causes AIDS), but it is perhaps the most violent. Victims of Ebola suffer internal bleeding and external bleeding, severe hemorrhaging, mental damage, are considered physically "drained" and suffer from vomiting of Ebola infected blood. Their ribcage are noted for collapsing into themselves along with their flesh. It is also a point of importance that, at least in non-human primates (specifically, African Green Monkeys) their flesh "melts" into a form similar to "soup."
So yes, Ebola is widely considered not only the most deadly virus in the world, but perhaps the worst disease. It is not as much of an efficient killer as a heart attack or even cancer, but those are not viral or bacterial diseases.
Depends which parts of Africa. In some parts, the deadliest disease is Malaria. In other parts, the deadliest disease is AIDs/HIV.
AIDS, and cancer
Not going to school. It's deadliest.
smallpox
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Somalia.
Heart disease, cancer, whooping cough,TB ,malaria, HIV/AIDS, meningitis and tetanus are some of the deadliest diseases.
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The world's deadliest disease is Ischaemic Heart Disease. This disease reduces blood flow to the heart. This is caused by coronary artery disease, smoking, aging, high cholesterol, and other factors. It is the most common cause of death among adults in the developed world.
The Tasmanian Devil.
Heart disease is the deadliest disease in America, being the leading cause of death for both men and women. It is responsible for a significant number of fatalities each year due to factors such as obesity, high blood pressure, and unhealthy lifestyle habits.
AnswerHumans are the deadliest, but if you're excluding them, then it's the mosquito because it spreads so much disease. Mosquitoes are responsible for the deaths of two million people every year. See the related link below.Number two is the Asian Cobra and three is the Australian Box Jellyfish.