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Is the central ,light staining region within a lymphoid follicle in spleen ,lymph nodes,or mucosal lymphoid tissue that forms during T cell-dependent humoral immune response and is the site of B cell and antibodies affinity maturation and antibodies class swiching .

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13y ago

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Explain the immune response in a lymph nodes?

First the structure of a lymph node... we have the cortex, paracortex and the medulla. It is made mainly of recticular cells, then lymphocytes and macrophage. So you have APCs presenting the antigen which enter lymph node via HEV, basically post-capillary venous swelling made of simple cuboidal cells. These allows things in blood to enter the lymph node. Then after that you have the APC interacting with B cells in the cortex and the T helper cells in paracortex. Both B and T cells get stimulated. B cells can either stay in cortex to form secondary follicles / germinal center or migrate to medullary cord to become plasma cells and secrete antibodies. The function of germinal center is to increase antibody affinity, isotope change (change classes) and differentiation and proliferation.


Do lymph node cells contain neutrophils?

no


What does the nail bed contain?

Lymph nodes


Does lymph contain bone marrow for hematopoiesis?

no


What cells cluster around the medullary sinuses?

The cells that cluster around the medullary sinuses in the lymph nodes are called reticular cells. These cells form a network of connective tissue, providing structural support for the lymph nodes. They also play a role in filtering lymph and facilitating immune responses.


Lymph Nodules can be either Primary Nodules or Secondary Nodules?

Yes, primary nodules don't have germinal centers(active B cells) while secondary nodules do.


What structural feature of lymphatic vessels is responsible for the forward movement of lymph?

One-way valves inside the lymphatic vessels prevent the backflow of lymph, helping to maintain a unidirectional flow towards the heart. This structural design ensures that lymph is pushed in the right direction, from the tissues towards the bloodstream.


Lymph nodes contain dense masses of?

Lymphocytes


Does a lymph contain white blood cells?

yes


What do both veins and lymph vessels contain?

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Which parts of the lymph node show increased activity when antibody production is high?

a. outer follicle b. germinal centres c. medullary cords d. sinuses


What does a Fatty center on axillary lymph node mean?

g