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Q: What missing protein causes sickle cell?
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What type of mutation causes sickle cell anemia substitution deletion insertion mutagen?

The type of mutation that causes a defect in the gene (causing sickle cell anaemia) is a substitution mutation.A single nucleotide substitution (A to T) in the β-globin gene causes the amino acid valine to replace glutamic acid. This changes the resulting protein, causing a haemoglobin with an abnormal shape to be created.


Why does sickle cell hemoglobin migrate slower than normal hemoglobin during electrophoresis?

because of the change of AA- in normal cell- from Glutamic acid (negativity charged) to Valine (uncharged) -in sickle cell- the charge will be missing in the sickle cell that why the electrophoresis will become slower because of the missing charge


What protein does does sickle-cell anemia affect?

Sickle cell disease is an inherited blood disorder that affects red blood cells.


What protein is not normal in people with sickle-cell disease?

It is Hemoglobin


What protein is not normal in people with sickle- cell disease?

Hemoglobin


Why does sickle cell hemoglobin migrate slower than normal hemoglobin during gel electrophoresis?

because of the change of AA- in normal cell- from Glutamic acid (negativity charged) to Valine (uncharged) -in sickle cell- the charge will be missing in the sickle cell that why the electrophoresis will become slower because of the missing charge


Can sickle cell anemia cause pneumonia?

no it dose not sickle cell anemia causes death only if African Americans


Mutation that causes sickle cell anemia?

pooo


When a mutation in the hemoglobin gene causes what disorder?

While technically there are more than one, the main one by far is sickle cell anemia.


How many amino acids need to be incorrect to prevent protein from working properly in sickle cell anemia?

Just one incorrect amino acid prevents protein from functioning properly in sickle cell anemia.


Is sickle cell anemia substitution random or does it occur under the direction of molecules that direct protein synthesis?

no.people have to get sickle cell from there mother or father and if you have a friend that have sickle cell you can`t catch thank you for leting me tell you your answer!! bye


What is the word for the genetic disorder that causes abnormal hemoglobin is known as?

sickle cell anemia. If you are only heterozygous for this disease it is simply called sickle trait.