The type of mutation that causes a defect in the gene (causing sickle cell anaemia) is a substitution mutation.A single nucleotide substitution (A to T) in the β-globin gene causes the amino acid valine to replace glutamic acid. This changes the resulting protein, causing a haemoglobin with an abnormal shape to be created.
because of the change of AA- in normal cell- from Glutamic acid (negativity charged) to Valine (uncharged) -in sickle cell- the charge will be missing in the sickle cell that why the electrophoresis will become slower because of the missing charge
Sickle cell disease is an inherited blood disorder that affects red blood cells.
It is Hemoglobin
Hemoglobin
because of the change of AA- in normal cell- from Glutamic acid (negativity charged) to Valine (uncharged) -in sickle cell- the charge will be missing in the sickle cell that why the electrophoresis will become slower because of the missing charge
no it dose not sickle cell anemia causes death only if African Americans
pooo
While technically there are more than one, the main one by far is sickle cell anemia.
Just one incorrect amino acid prevents protein from functioning properly in sickle cell anemia.
no.people have to get sickle cell from there mother or father and if you have a friend that have sickle cell you can`t catch thank you for leting me tell you your answer!! bye
sickle cell anemia. If you are only heterozygous for this disease it is simply called sickle trait.