Bilirubin is a breakdown product of heme (a part of haemoglobin in red blood cells). The liver is responsible for clearing the blood of bilirubin. It does this by the following mechanism: bilirubin is taken up into hepatocytes, conjugated (modified to make it water-soluble), and secreted into the bile, which is excreted into the intestine. Increased total bilirubin causes jaundice, and can signal a number of problems: 1. Prehepatic: Increased bilirubin production. This can be due to a number of causes, including hemolytic anemias and internal hemorrhage. 2. Hepatic: Problems with the liver, which are reflected as deficiencies in bilirubin metabolism (e.g. reduced hepatocyte uptake, impaired conjugation of bilirubin, and reduced hepatocyte secretion of bilirubin). Some examples would be cirrhosis and viral hepatitis. 3. Posthepatic: Obstruction of the bile ducts, reflected as deficiencies in bilirubin excretion. (Obstruction can be located either within the liver or in the bile duct.)
Elevated levels of indirect bilirubin in liver function tests indicate excessive breakdown of red blood cells. Indirect bilirubin is a byproduct of the breakdown of hemoglobin from red blood cells, and increased levels suggest an increased rate of red blood cell destruction.
Yes, carbon monoxide poisoning can lead to increased levels of bilirubin in the bloodstream. This is because carbon monoxide can impair the function of red blood cells, leading to an accumulation of bilirubin, which is a byproduct of the breakdown of red blood cells. If left untreated, high levels of bilirubin can cause jaundice and other serious health problems.
There is no "cure" for haemophilia, only treatment with the appropriate clotting factors.
From the glossary of medical terms the answer is: BILIRUBIN
The color of Bilirubin is orange Bilirubin is an orange color pigment in the bile
increase levels of bilirubin in blood due to increased production as in rapid destruction of red blood cells. more commonly it is due to decreased elimination of bilirubin because of liver disease.
Jaundice is caused by the rapid breakdown of red blood cells which leads to increased levels of bilirubin.
Bilirubin is the pigment that makes feces brown."Failure of the liver cells to excrete bile, or obstruction of the bile ducts, can cause an increased amount of bilirubin in the body fluids and thus lead to obstructive or regurgitation jaundice.Another type of jaundice results from excessive destruction of erythrocytes (hemolytic or retention jaundice). The more rapid the destruction of red blood cells and the degradation of hemoglobin, the greater the amount of bilirubin in the body fluids.Most bilirubin is excreted in the feces. A small amount is excreted in the urine as urobilinogen."answers.com
Possibly - One of the symptoms is Jaundice (yellowing of the eyes and skin), due to increased bilirubin in the blood.
Haemophilia (also spelled hemophilia) is genetic disorder. It is more licely for a male to get it than female. About one of 5,000-10,000 male babies are born with Haemophilia A. About one of 20,000-34,000 male babies are born with Haemophilia B.
Bilirubin