Citrate in blood binds to calcium ions, forming complexes that are not available for biological functions. This decreases the amount of free calcium in the blood, leading to hypocalcemia. Additionally, citrate can chelate calcium in the blood, further reducing the level of ionized calcium available for use in blood clotting and nerve function.
Blood contains high levels of citrate. Calcium gluconate helps counteract or buffer the effect of the citrate which can include chelating, inability to coagulant or clot which can cause hypocalcemia, and citrate toxicity due to the lover's slow processing of citrate.
Hypocalcemia can cause depression
correct me if im wrong... it's because each unit of blood contains citrate. it acts as a chelating agent and anti coagulant, thus cause hypocalcemia. another, it will prevent citrate toxicity because the liver metabolizes this slowly. each unit may contain about 3g of citrate. am i right?
Deffinately. It depends greatly on how low your actual calcium is but I suffer from hypocalcemia and my bones ache alot along with muscle cramps and tetany.
slow down or will cause bradycardia. calcium is essential in muscle contraction.
One common cause of hypocalcemia is low Vitamin D, frequently seen in areas of the country where sunshine is absent or rare. It can also be caused by thyroid dysfunction, or by renal failure.
Hypocalcemia
Yes, hemolysis can cause hypocalcemia due to intracellular release of potassium, magnesium, and phosphate during red blood cell breakdown. These electrolyte shifts can lead to binding of ionized calcium and result in decreased levels in the blood.
Don't know about magnesium citrate, but magnesium tablets sure did, in my case.
The prognosis for correcting hypocalcemia is excellent. However, the eye damage that may result from chronic hypocalcemia cannot be reversed.
Treatment of hypocalcemia typically involves calcium supplementation, usually in the form of calcium carbonate or calcium gluconate depending on the severity of the deficiency. In critical cases, intravenous calcium may be administered. Identifying the underlying cause of hypocalcemia is important to prevent recurrence.