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Hemophilia is generally more severe in males because it is an X-linked recessive disorder, meaning that men have only one X chromosome, while women have two. If a woman possesses one defective gene for hemophilia on one X chromosome, she may still have a functional gene on her other X chromosome, often resulting in milder symptoms. However, if a woman inherits two mutated X chromosomes, she can experience severe hemophilia, leading to a higher risk of fatal complications compared to men. Additionally, women with hemophilia may face challenges related to reproductive health and bleeding during childbirth, increasing the potential for life-threatening situations.

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1w ago

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