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The peptide hormone is used to include hormones that are peptides,proteins,glycoprotein,and modified amino acids.

peptide hormones binds to a receptor protein in the target cell's plasma membrane; a realy system leads to conversion of ATP to cAMP(cyclic adenosine mono phosphate).peptide hormones are the first messenger and cAMP and calcium are the second messengers.

peptide hormones does not enter the cell; second messenger sets an enzyme cascade in motion.

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