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Naproxen is an anti-inflammatory medication. Tramadol, although it does stimulate the opiate receptors it is not considered an opiate. They are in completely different classes of pain medication. However, several recent studies have determined that combining tramadol with an NSAID, such as naproxen or ibuprofen, produces a far greater benefits than using either drug separately.

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http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1693661

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