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Where would you not find cholinergeric nicotinic receptor?
all parasympathetic target organs
Where would you find a cholinergeric nicotinic receptor?
all parasympathetic target organs
Difference between muscarinic and nicotinic receptors?
1) nicotinic acetyle choline receptors are ligand gated ion channels, where as mucarinic Ach receptors are G-proteins coupled receptors system. 2) nicotine is a agonist/ muscarine( a toxin produced by certain mushrooms) is a agonist. 3) action of nicotine is fast(1-2msec)/action of muscarinic is slow (100-250msec). 4) in case of nicotinic ach receptor, subtypes based on different subunit composition.muscle and neuronal classification/in case of muscarinic receptor at least 5 receptors subtype have been described by molecular cloning. 5) in case of nicotinic receptor agonist effects blocked by tubocuranine/in case of muscarinic receptor agonist effects blocked by atropine. 6) nicotinic receptor found at neuro muscular junction of skeletal muscle, on the post ganglion neurons of the parasympathetic nervous system and on many neurons on the brain(hypothalamus)/muscarinc receptor found at neuromuscular junction of cardiac and smooth muscle as well as on glands and on the post ganglionic neurons of the sympathetic nervous system.
What statement describes nicotinic acetylcholine ACh receptors as opposed to muscarinic ACh receptors?
Nicotinic ACh receptors are ionotropic receptors that mediate fast neurotransmission, while muscarinic ACh receptors are metabotropic receptors that modulate cell signaling through G-proteins. Nicotinic receptors are typically found at neuromuscular junctions and in the central nervous system, whereas muscarinic receptors are more widely distributed in peripheral tissues and the brain.
Describe the interaction of acetylcholine and calcium ions in stimulating muscle contraction?
The acetylcholine diffuses across the synapse and binds to and activates nicotinic acetylcholine receptors on the motor end plate of the muscle cell. Activation of the nicotinic receptor opens its intrinsic sodium/potassium channel, causing sodium to rush in and potassium to trickle out.
How many different kinds of receptors are there for acetylcholine?
There are two main types of receptors for acetylcholine: muscarinic receptors, which are G-protein coupled receptors, and nicotinic receptors, which are ligand-gated ion channels. Each type of receptor is further classified into different subtypes based on their structure and function.
What receptor type is exemplified by opening a channel to let sodium into the cell?
The receptor type exemplified by opening a channel to let sodium into the cell is the ligand-gated ion channel. When a specific ligand, such as a neurotransmitter, binds to the receptor, it causes a conformational change that opens the channel, allowing sodium ions (Na+) to flow into the cell. This influx of sodium typically leads to depolarization of the cell membrane, which can trigger an action potential in neurons. Examples of such receptors include the nicotinic acetylcholine receptor and the glutamate receptor.
How does curare cause muscle paralysis?
Curare is a competitive inhibitor of acetylcholine. It fights with acetycholine for postsynaptic receptors.
What is another name for nicotinic acid?
The answer is "Niacin"
What is the formula for niacinamide?
Niacinamide is also known as niacinamide and nicotinic amide. It is the amide of nicotinic acid. Its formula is C6H6N2O.
Can nicotinic kill you?
60 mgs will kill you
What kind of acid is in coffee?
Nicotinic Aacid
