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They are the same thing; buproprion always comes as buproprion hcl or occasionally buproprion hbr. The different names are essential just different brand names. So 150mg will be more effective than 100mg for weight loss.

That said, only 28% of people lose significant weight on Buproprion, and most of them had recently gained weight due to depression. It is most effective as part of a controlled diet and exercise plan, because it will reduce the psychological pain of dieting by keeping your dopamine up without food, and it will give you more energy to exercise. If you aren't clinically depressed and don't change your lifestyle, the average weight loss after a year on Buproprion is 1.8lbs.

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