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Thomas Jefferson didn't play a role in McCulloch v. Maryland, (1819). He retired from politics in 1809, at the end of his second term as President, and became an advocate for higher education. Jefferson believed a well-educated populace was important to the success of democracy (or a republic).

In 1819, the year McCulloch v. Maryland was decided, he helped found the University of Virginia (officially chartered as The Rector and Visitors of the University of Virginia), in Charlottesville. The public university was constructed on farmland once owned by then-President James Monroe. Thomas Jefferson, James Madison and James Monroe sat on the school's first Board of Visitors (board of directors).

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