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Of all the congenital Heart diseases, patent ductus arteriosis (PDA) is the only disease that can be treated.
The PDA treatment algorithm includes the following:
- Fluid restriction
- Diuretics
- Non-steroidal anti-inflammatory drugs (NSAIDs) [See elaboration below.]
- Indomethacin, OR
- ibuprofen
- Surgical ligation
- When NSAIDs fail to treat the PDA.
NSAIDs Comparison:
- Indomethacin
- Doses:
- Initial dose: 0.2 mg/Kg Intravenously (IV)
- Subsequent doses varies
- Post natal age - increase dose with increased age
- Infant renal function - increase dosing interval for poor renal function.
- Doses:
- Ibuprofen
- Doses:
- Initial dose: 10 mg/Kg IV
- Subsequent dose: 5 mg/Kg IV daily for 2 days.
- Doses:
- Note: Calculate dosing for both drugs using the infant's birth weight.
- COX-1 inhibition (COX-1 is responsible for inflammation, so higher inhibition of COX-1 is preferred.)
- Indomethacin > Ibuprofen
- Stability
- Indomethacin (12 days) > Ibuprofen (30 minutes)
- Degree of protein binding (May cause accumulation of bilirubin in the brain, otherwise known as "kernicterus," which is associated with cerebral palsy.)
- Occurs in both NSAIDs
- More incidents reported on ibuprofen.
- Efficacy in treating PDA
- Indomethacin = Ibuprofen
Indomethacin is generally the preferred medication for PDA treatment.
- Adverse Effects from Both NSAIDs
- Oliguria, renal failure
- Gastrointestinal bleeding
- Bowel perforation
- Necrotizing enterocolitis
- Intraventricular hemorrhage
- Thrombocytopenia
- Contraindication to use NSAIDs (Do not use NSAIDs, if the following occurs.)
- Necrotizing enterocolitis
- Intraventricular hemorrhage
- Active bleeding
- Thrombocytopenia
- Impaired renal functions
What else can I help you with?
What structure is used to connect the aorta and the pulmonary artery in fetal circulation?
Ductus arteriosus
What are Patent ductus arteriosis signs and sympoms?
What are the signs and symptoms of patent ductus arrteriosis? Fast breathing or shortness of breath. Poor feeding and poor weight gain.
What infants could be injured by mechanical ventilation?
Newborns with patent ductus arteriosis, a handicap affecting the pulmonary artery, are more likely to suffer pulmonary hemorrhage from mechanical ventilation.
How is patent ductus arteriosus treated in premature infants?
Patent ductus arteriosus in premature infants is typically managed using medication such as indomethacin or ibuprofen to help close the ductus. In cases where medication is ineffective or contraindicated, surgical closure may be necessary. Monitoring for potential complications and close follow-up are important aspects of the treatment plan.
What is an abnormal opening between the pulmonary artery and the aorta?
Patent Ductus Arteriosus
What are the symptoms of Patent ductus arteriosus?
A small Patent ductus arteriousus doesn't cause too many symptoms. But a large Patent ductus arteriousus includes symptoms of poor growth, shortness of breath, poor eating habits and fast breathing.
What does the medical abbreviation PDA mean?
Patent Ductus Arteriosus
What is the CPT code for ligation patent ductus arteriosus?
33820
What is the medical condition patent ductus arteriosus in premature infants?
Patent ductus arteriosus is a condition in which the duct that channels blood between two main arteries does not close after the baby is born.
Cpt code for ligation patent ductus arteriosus?
For ligation of patent ductus arteriosus assign 33820 by division assign 33822 if younger than 18 and 33824 if 18 and older C McGlynn,CPC
What murmur radiates to the back?
Patent ductus arteriosus, or PDA, is a type of heart murmur that radiates to the back. It occurs when an infant's ductus arteriosus does not close after birth.
What is passageway between the aorta and the pulmonary artery remains open after birth?
Patent Ductus Arteriosus
