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The female ferret is an induced ovulator, meaning she must mate to terminate estrus. If she is not bred, she will remain in estrus which in time will result in excess estrogen in her body leading to a disorder know as estrogen-induced anemia, which can lead to leukemia and finally death.

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Female ferrets will stay in heat until mated (with an unaltered or vasectomized male or a "jill jab" from a veterinarian). If she is not mated, she will develop anemia due to excess estrogen and could eventually die.


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